Results 41 to 50 of about 69,381 (252)
eLife, 2020 Vesicle fusion is mediated by assembly of SNARE proteins between opposing membranes. While previous work suggested an active role of SNARE transmembrane domains (TMDs) in promoting membrane merger (Dhara et al., 2016), the underlying mechanism remained ...
Madhurima Dhara +5 more
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Membrane curvature induced by polymer adsorption [PDF]
Physical Review E, 2001 The phenomena resulting from interaction between polymers and membranes pose important problems for biological applications. Based on a scaling theory, we investigate the spontaneous curvature of a membrane induced by either flexible or semiflexible chain adsorption.
Kim, YW Kim, Yong Woon, Sung, WY
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Membranes, 2017 The shape and composition of a membrane directly regulate the localization, activity, and signaling properties of membrane associated proteins. Proteins that both sense and generate membrane curvature, e.g., through amphiphilic insertion motifs ...
Kenneth Lindegaard Madsen, Rasmus Herlo
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Interplay of membrane crosslinking and curvature induction by annexins
Scientific Reports, 2022 Efficient plasma membrane repair (PMR) is required to repair damage sustained in the cellular life cycle. The annexin family of proteins, involved in PMR, are activated by Ca2+ influx from extracellular media at the site of injury. Mechanistic studies of
Anna Mularski +6 more
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Frontiers in Physiology, 2022 Piezo1 is a membrane nonspecific cation channel involved in red blood cells (RBCs) in the regulation of their volume. Recently, it was shown that it is distributed on the RBC membrane in a nonuniform manner.
Bojan Božič +2 more
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Monomeric Synucleins Generate Membrane Curvature [PDF]
Journal of Biological Chemistry, 2013 Synucleins are a family of presynaptic membrane binding proteins. α-Synuclein, the principal member of this family, is mutated in familial Parkinson disease. To gain insight into the molecular functions of synucleins, we performed an unbiased proteomic screen and identified synaptic protein changes in αβγ-synuclein knock-out brains.
Christopher H, Westphal +1 more
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Cells, 2020 The plasma membrane surrounds every single cell and essentially shapes cell life by separating the interior from the external environment. Thus, maintenance of cell membrane integrity is essential to prevent death caused by disruption of the plasma ...
Poul Martin Bendix +16 more
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Inhomogeneous Canham–Helfrich Abscission in Catenoid Necks under Critical Membrane Mosaicity
Membranes, 2023 The mechanical effects of membrane compositional inhomogeneities are analyzed in a process analogous to neck formation in cellular membranes. We cast on the Canham–Helfrich model of fluid membranes with both the spontaneous curvature and the surface ...
José Antonio Santiago, Francisco Monroy
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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Models for membrane curvature sensing of curvature generating proteins [PDF]
Pramana, 2020 13 pages, 3 ...
T V Sachin Krishnan +2 more
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