Results 51 to 60 of about 1,339,571 (248)
Inhomogeneous Canham–Helfrich Abscission in Catenoid Necks under Critical Membrane Mosaicity
Membranes, 2023 The mechanical effects of membrane compositional inhomogeneities are analyzed in a process analogous to neck formation in cellular membranes. We cast on the Canham–Helfrich model of fluid membranes with both the spontaneous curvature and the surface ...
José Antonio Santiago, Francisco Monroy
doaj +1 more source
Micro-machined membrane deformable mirrors for cryogenic adaptive optics [PDF]
, 2002 In this Thesis, the suitability of 37 actuator Micro-machined membrane deformable mirrors (MMDM) for adaptive optics at cryogenic temperatures is evaluated. A method is described to safely cool MMDMs to 78K. The initial surface figures of three MMDMs are
Dyson, H.M., Dyson, Harold Michael
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Extracellular domain 2 of TSPAN4 governs its functions
Biophysical ReportsTetraspanin 4, a protein with four transmembrane helices and three connecting loops, senses membrane curvature and localizes to membrane tubes. This enrichment in tubular membranes enhances its diverse interactions.
Raviv Dharan, Alisa Vaknin, Raya Sorkin
doaj +1 more source
Membrane curvature sensing of the lipid-anchored K-Ras small GTPase
Life Science Alliance, 2019 Proteolipid nanoassemblies of K-Ras and lipids in the plasma membrane sense changing membrane curvature architecture and convert mechanical perturbations to mitogenic signaling.
Hong Liang +12 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Membrane curvature controls dynamin polymerization
, 2010 International audienceThe generation of membrane curvature in intracellular traffic involves many proteins that can curve lipid bilayers. Among these, dynamin-like proteins were shown to deform membranes into tubules, and thus far are the only proteins ...
Nassoy, Pierre +6 more
core +5 more sources
Generating Membrane Curvature at the Nuclear Pore: A Lipid Point of View
Cells, 2022 In addition to its structural role in enclosing and protecting the genome, the nuclear envelope (NE) forms a highly adaptive communication interface between the cytoplasm and the nuclear interior in eukaryotic cells.
Bas W. A. Peeters +2 more
doaj +1 more source
Mean curvature flow with triple junctions in higher space dimensions [PDF]
, 2012 We consider mean curvature ow of n-dimensional surface clusters. At (
Garcke, Harald +2 more
core +1 more source