Results 111 to 120 of about 234,049 (261)

Characterization of ultrafiltration membranes by tracer's retention:Comparison of methods sensitivity and reproducibility [PDF]

, 2010
Previous studies have shown that the absolute membrane cut-off and the value quoted by the manufacturers may be very different because of differences in methodologies and testing conditions.
Causserand, Christel, Lorain, Olivier, Pierre, Gwenaelle, Rapenne, Sophie, Sauvade, Patrick, Schrotter, Jean-Christophe   +5 more
core   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A saposin-lipoprotein nanoparticle system for membrane proteins. [PDF]

, 2016
A limiting factor in membrane protein research is the ability to solubilize and stabilize such proteins. Detergents are used most often for solubilizing membrane proteins, but they are associated with protein instability and poor compatibility with ...
Armache, Jean-Paul, Briggs, John AG, Cheng, Yifan, Flayhan, Ali, Frauenfeld, Jens, Garoff, Henrik, Guettou, Fatma, Jegerschöld, Caroline, Löving, Robin, Löw, Christian, Moberg, Per, Nordlund, Pär, Sonnen, Andreas F-P, Zhu, Lin   +13 more
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Polyaniline composite membranes synthesis in presence of various acid dopants for pressure filtration [PDF]

, 2017
Polyaniline is a conductive polymer that is recently used as a material in producing a pressure filtration membrane. Polyaniline can be doped in various acids as dopants of different sizes and shapes to modify its inherent properties to produce membrane ...
Asif Ali Qaiser, Farah Adlyna Mey Efdi, Izzati Izni Yusoff, Mohd Usman Mohd Junaidi, null null, Rosiah Rohani   +5 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Research progress of fouling mitigation in photocatalysis coupled membrane filtration systems

Gongye shui chuli
Photocatalysis is an environmentally friendly advanced oxidation technology, which can effectively degrade organic pollutants. Membrane-based technology as an efficient separation approach has been widely used in the field of water treatment.
WANG Guohui, YAN Jiaguo, Li Yanli, WANG Xin, CHEN Mei   +4 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Zeolite-PAN/PVDF composite nanofiber membranes for highly efficient and selective removal of cationic dyes from wastewater

Case Studies in Chemical and Environmental Engineering
This study presents a novel composite nanofiber membrane combining polyacrylonitrile/polyvinylidene fluoride (PAN/PVDF) electrospun nanofibers with locally sourced zeolite from Sumatera, Indonesia, for pollutant dye filtration.
Muhamad F. Arif, Sephia Amanda Muhtar, Cindy Siburian, Kurniawan Deny Pratama Marpaung, Nursidik Yulianto, Fatwa F. Abdi, Tarmizi Taher, Hutomo Suryo Wasisto, Aditya Rianjanu   +8 more
doaj   +1 more source

Ageing of polysulfone membranes in contact with bleach solution: Role of radical oxidation and of some dissolved metal ions [PDF]

, 2008
In water production plants using membrane processes, contact with chemicals such as chlorine plays an important role in membrane ageing. This experimental study was aimed at gaining a better understanding of the effect of hypochlorite cleaning solutions ...
Aimar, Pierre, Causserand, Christel, Lafaille, Jean-Pierre, Rouaix, Sandrine   +3 more
core   +3 more sources