Results 111 to 120 of about 1,549,978 (301)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Refining sugarcane juice by an integrated membrane process: Filtration behavior of polymeric membrane at high temperature

, 2016
Application of membrane filtration to sugarcane juice refining is appealing because it can eliminate the usage of chemicals, achieve continuous and automated production, as well as produce superior quality of juice. However, some technical problems, such
Chen, Xiangrong, Wan, Yinhua, Hang, Xiaofeng, Qi, Benkun, Luo, Jianquan, Song, Weijie, Zhai, Wei   +6 more
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Vibratory shear enhanced membrane process and its application in starch wastewater recycle [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2002
Membrane application in wastewater is gaining significant popularity. Selecting the right membrane and filtration technique is an important consideration to ensure a successful system development and long term performance.
Kazi Sarwar Hasan, Chettiyappan Visvanathan, Prapan Ariyamethee, Sumaporn Chantaraaumporn, Pongchakas Moongkhumklang   +4 more
doaj  

Submerged hollow fibre membrane filtration with transverse and longitudinal vibrations

, 2013
A comparative study of transverse and longitudinal vibrations of submerged hollow fibre membranes for fouling control was carried out in this paper. The same membrane module was adopted in the comparison, and the reactor geometry was identical.
Fane, Anthony Gordon, Law, Adrian Wing-Keung, Li, Tian (CEE)   +2 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Optimisation of membrane technology for water reuse [PDF]

, 2011
Increasing freshwater scarcity is making reclamation of wastewater effluent more economically attractive as a means of preserving freshwater resources.
Raffin, Marie
core   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Morphological Engineering of Electrospun Recycled Polyethylene Terephthalate (r-PET) Nanofibrous Membranes for Sustainable Air Filtration: A Critical Review

Membranes
The growing demand for high-performance air filtration materials, coupled with increasing concerns over plastic waste accumulation, has accelerated interest in sustainable filtration technologies.
Wei Lin Ng, Abu Bakar Sulong, Eng-Poh Ng, Soon Huat Tan   +3 more
doaj   +1 more source