Results 101 to 110 of about 234,049 (261)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Optimization of Inorganic Ceramic Membrane Filtration Process for Tea Enzymes

Shipin gongye ke-ji
In order to enhance the clarity of tea enzymes while maximizing the preservation of their functional components during the clarification process, this experiment utilized tea enzymes derived from summer and autumn tea fermentation as the primary material.
Chunyan LI, Fuxiao WEI, Yu WANG, Chaoju ZHANG, Tiantian XU, Daoping WANG   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Enhanced performance of submerged membrane microfiltration by aeration and backwash for mitigating particle fouling

Chemical Engineering Journal Advances
Submerged membrane filtration (SMF) has been widely used for wastewater treatment and biochemical separation by integrating advanced filtration systems.
Su-En Wu, Chieh-Hung Kuo
doaj   +1 more source

Fate of micronutrients and heavy metals in digestate processing using vibrating reversed osmosis as resource recovery technology [PDF]

, 2019
This study aims to evaluate the full-scale performance of vibrating membrane filtration (VSEP) technology in resource recovery from the liquid fraction of digestates, while reducing macronutrient concentrations down to dischargeable water.
Darveau, Olivier, Meers, Erik, Vaneeckhaute, Céline   +2 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The preparation and characterization of alumina membranes with ultrafine pores 2. The formation of supported membranes [PDF]

, 1985
Supported γ-A12O3 membranes are prepared by a dipping procedure. According to this method, a capillary pressure drop is created by bringing a microporous ceramic support into contact with a boehmite (γ-A1OOH) sol. This pressure drop forces the dispersion
Burggraaf, A.J., Leenaars, A.F.M.
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Evaluation of the ability to control ammonium, nitrate and nitrite in water using membrane filtration technology

Tạp chí Kiểm nghiệm và An toàn thực phẩm
Domestic water sources in rural areas could be polluted by ammonium, nitrite and nitrate. These compounds affected to human health. Therefore, development of membrane filtration system to control the above pollution parameters is essential. In this study,
Dinh Tung Duong, Pham Thu Thao, Do Khac Uan   +2 more
doaj   +1 more source

PREPARATION MICRO-FILTRATION CERAMIC MEMBRANE FROM NATURAL ZEOLITE FOR PROCION RED MX8B AND METHYLENE BLUE FILTRATION

Alchemy, 2015
The study of ceramic membrane fabrication from natural zeolite and its utilization for filtration of procion red MX8B and methylene blue has been investigated.
Dyah Choiriyah, Esfi Riandini, Arinta Wulandari, Oktaviana Dewi Indah, P Alifia, Harista Rachma, Edi Pramono   +6 more
doaj   +1 more source