Results 71 to 80 of about 1,549,978 (301)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Dead-end and crossflow microfiltration of yeast and bentonite suspensions: experimental and modelling studies incorporating the use of artificial neural networks [PDF]

open access: yes, 2008
The applicability of artificial neural networks (ANNs) and semi-empirical modelling techniques for correlation and prediction of the filtration characteristics of microfiltration systems was assessed.
Ní Mhurchú, Jenny
core   +2 more sources

Membrane filtration of clarified juice [PDF]

open access: yes, 2010
A membrane filtration plant using suitable micro or ultra-filtration membranes has the\ud potential to significantly increase pan stage capacity and improve sugar quality.\ud Previous investigations by SRI and others have shown that membranes will remove\
Steindl, Rod J.   +5 more
core  

Aeration and hydrodynamics in submerged membrane bioreactors [PDF]

open access: yes, 2011
Membrane bioreactor (MBR) is already a well-developed wastewater treatment process for both municipal and industrial applications. Nonetheless, membrane fouling remains a significant problem for its wider development.
Etienne Braak   +7 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Dead-end filtration of natural organic matter: experimental evidence of critical conditions [PDF]

open access: yes, 2005
The development of membrane technology has reached a state whereby operational optimisation is becoming the major issue to both researchers and industrial operators.
Jefferson, Bruce   +2 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

The performance of bovine serum albumin filtration by using polyethersulfone-Tetronic 304 blend Ultrafiltration Membrane [version 2; peer review: 2 approved]

open access: yesF1000Research, 2019
Background: Membrane technology has been widely applied for protein purification. In applications for protein separation, a membrane with stable filtration performance is necessary.
Fachrul Razi   +2 more
doaj   +1 more source

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