Results 141 to 150 of about 133,090 (338)

Structural Basis and Mechanism of a Unique Haemophore in the Haem‐Iron Acquisition by Riemerella anatipestifer

open access: yesAdvanced Science, Volume 12, Issue 13, April 3, 2025.
This study reveals the structural basis and mechanism of RhuH as a haemophore in Riemerella anatipestifer. Secreted by outer membrane vesicles (OMVs), RhuH captures haem with high affinity from host hemoglobin in two forms: a) released from OMVs, binding and transferring haem to outer membrane receptor, and b) haem‐bound on the OMVs surface, returning ...
Mengying Wang   +19 more
wiley   +1 more source

Lysosomal Membrane Glycoproteins in Platelets [PDF]

open access: yesThrombosis and Haemostasis, 1992
Hans Clevers, Marcel J Metzelaar
openaire   +2 more sources

3D‐Printed Biomimetic Vascular Scaffold Crosslinked with Heparan Sulfate for Sustained Release of PDGFB‐LG4 Fusion Protein Promotes Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Fusion protein PDGFB‐LG4 exhibits superior osteoinductive and angiogenic activity compared to PDGFB. The PCLHS‐PDGFB‐LG4 scaffold, featuring perfusable and permeable vascular‐like networks, promotes angiogenesis and osteogenesis through the sustained release of PDGFB‐LG4, thereby accelerating the bone defect repair process.
Jiahua Duan   +6 more
wiley   +1 more source

Engineering the Immune Response to Biomaterials

open access: yesAdvanced Science, EarlyView.
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam   +12 more
wiley   +1 more source

A Facile Strategy to Restore the Optic Nerve Functionality Using an Injectable Conducting Hydrogel

open access: yesAdvanced Science, EarlyView.
An injectable conductive polymer hydrogel from poly (3,4‐ethylenedioxythiophene) (PEDOT) is developed to facilitate the recovery of electrophysiological function in injured optic nerve. The hydrogel can be injected directly at the injury site and spontaneously gel in place.
Changchun Yu   +12 more
wiley   +1 more source

Deciphering the Metabolic Impact and Clinical Relevance of N‐Glycosylation in Colorectal Cancer through Comprehensive Glycoproteomic Profiling

open access: yesAdvanced Science, EarlyView.
The comprehensive proteomic and N‐glycoproteomic analyses of 45 colorectal cancer tissues with matched normal adjacent tissues identified 7125 intact N‐glycopeptides from 704 glycoproteins. A glycosylation site‐protein function network revealing metabolic dysregulation is constructed and a model differentiating tumors from normal tissues is developed ...
Guobin Liu   +10 more
wiley   +1 more source

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