Lipidomimetic Compounds Act as HIV-1 Entry Inhibitors by Altering Viral Membrane Structure
Frontiers in Immunology, 2018 The envelope of Human Immunodeficiency Virus type 1 (HIV-1) consists of a liquid-ordered membrane enriched in raft lipids and containing the viral glycoproteins.
Jon Ander Nieto-Garai +21 more
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Human galectin-1 and galectin-3 promote Tropheryma whipplei infection
Gut Microbes, 2021 Tropheryma whipplei, is an actinobacterium that causes different infections in humans, including Whipple’s disease. The bacterium infects and replicates in macrophages, leading to a Th2-biased immune response. Previous studies have shown that T. whipplei
Diyoly Ayona +7 more
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Tomato spotted wilt virus glycoproteins induce the formation of endoplasmic reticulum- and Golgi-derived pleomorphic membrane structures in plant cells [PDF]
, 2008 Tomato spotted wilt virus (TSWV) particles are spherical and enveloped, an uncommon feature among plant infecting viruses. Previous studies have shown that virus particle formation involves the enwrapment of ribonucleoproteins with viral glycoprotein ...
Denecke, J. +5 more
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Herpesvirus glycoproteins undergo multiple antigenic changes before membrane fusion.
PLoS ONE, 2012 Herpesvirus entry is a complicated process involving multiple virion glycoproteins and culminating in membrane fusion. Glycoprotein conformation changes are likely to play key roles.
Daniel L Glauser +2 more
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Emerging Microbes and Infections, 2023 Viral envelope glycoproteins are crucial for viral infections. In the process of enveloped viruses budding and release from the producer cells, viral envelope glycoproteins are presented on the viral membrane surface as spikes, promoting the virus's next-
Changqing Yu +7 more
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Super-resolution microscopy reveals specific recruitment of HIV-1 envelope proteins to viral assembly sites dependent on the envelope C-terminal tail [PDF]
, 2013 The inner structural Gag proteins and the envelope (Env) glycoproteins of human immunodeficiency virus (HIV-1) traffic independently to the plasma membrane, where they assemble the nascent virion. HIV-1 carries a relatively low number of glycoproteins in
Heilemann, Mike +4 more
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Profiling the Bisecting N-acetylglucosamine Modification in Amniotic Membrane via Mass Spectrometry
Genomics, Proteomics & Bioinformatics, 2022 Bisecting N-acetylglucosamine (GlcNAc), a GlcNAc linked to the core β-mannose residue via a β1,4 linkage, is a special type of N-glycosylation that has been reported to be involved in various biological processes, such as cell adhesion and fetal ...
Qiushi Chen +14 more
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Receptor-Targeted Nipah Virus Glycoproteins Improve Cell-Type Selective Gene Delivery and Reveal a Preference for Membrane-Proximal Cell Attachment. [PDF]
PLoS Pathogens, 2016 Receptor-targeted lentiviral vectors (LVs) can be an effective tool for selective transfer of genes into distinct cell types of choice. Moreover, they can be used to determine the molecular properties that cell surface proteins must fulfill to act as ...
Ruben R Bender +7 more
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Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity
Viruses, 2021 Host plasma membrane protein SERINC5 is incorporated into budding retrovirus particles where it blocks subsequent entry into susceptible target cells.
William E. Diehl +6 more
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Scientific Reports, 2023 Tuberculosis (TB) remains one of the most afflictive bacterial infections globally. In high burden TB countries, surveillance, diagnosis and treatment of drug resistant TB (RR and X/MDRTB) display a crucial public health challenge. Therefore, we need new
Shamsi Yari +5 more
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