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Fusogenic structural changes in arenavirus glycoproteins are associated with viroporin activity.
Many enveloped viruses enter host cells by fusing with acidic endosomes. The fusion activity of multiple viral envelope glycoproteins does not generally affect viral membrane permeability.
You Zhang+4 more
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Membrane curvature regulates the spatial distribution of bulky glycoproteins
MUC1 is a heavily glycosylated protein on the cell surface. Here the authors show that MUC1 prefers negative over positive membrane curvature due to its bulky size, enabling MUC1 to avoid endocytosis and surface removal based on curvature preference.
Chih-Hao Lu+7 more
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Human respiratory syncytial virus (HRSV) is an enveloped RNA virus that assembles and buds from the plasma membrane of infected cells. The ribonucleoprotein complex (RNP) must associate with the viral matrix protein and glycoproteins to form newly ...
Melissa Batonick, Gail W. Wertz
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Paramyxoviruses are a family of negative sense RNA viruses whose members cause serious diseases in humans, such as measles virus, mumps virus and respiratory syncytial virus; and in animals, such as Newcastle disease virus and rinderpest virus ...
Farah El Najjar+2 more
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Membrane Glycoproteins of Enveloped Viruses
This chapter focuses on the recent information of the glycoprotein components of enveloped viruses and points out specific findings on viral envelopes. Although enveloped viruses of different major groups vary in size and shape, as well as in the molecular weight of their structural polypeptides, there are general similarities in the types of ...
Maurice C. Kemp, Richard W. Compans
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Paranodin, a Glycoprotein of Neuronal Paranodal Membranes [PDF]
Ranvier nodes are flanked by paranodal regions, at the level of which oligodendrocytes or Schwann cells interact closely with axons. Paranodes play a critical role in the physiological properties of myelinated nerve fibers. Paranodin, a prominent 180 kDa transmembrane neuronal glycoprotein, was purified and cloned from adult rat brain, and found to be ...
Pascal Ezan+8 more
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The processes of cell attachment and membrane fusion of Herpes Simplex Virus 1 involve many different envelope glycoproteins. Viral proteins gC and gD bind to cellular receptors.
Frauke Beilstein+5 more
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Membrane-bound glycoproteins [PDF]
Membrane Glycoproteins: A Review of Structure and Function. By R. Colin Hughes. Pp. 367. (Butterworth: London and Boston, Massachusetts, March 1976.) £15.00.
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Towards Understanding KSHV Fusion and Entry
How viruses enter cells is of critical importance to pathogenesis in the host and for treatment strategies. Over the last several years, the herpesvirus field has made numerous and thoroughly fascinating discoveries about the entry of alpha-, beta-, and ...
Stephen J. Dollery
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Envelope glycoproteins from genetically-divergent virus families comprise fusion peptides (FPs) that have been posited to insert and perturb the membranes of target cells upon activation of the virus-cell fusion reaction.
Igor de la Arada+7 more
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