Lipidomimetic Compounds Act as HIV-1 Entry Inhibitors by Altering Viral Membrane Structure
Frontiers in Immunology, 2018 The envelope of Human Immunodeficiency Virus type 1 (HIV-1) consists of a liquid-ordered membrane enriched in raft lipids and containing the viral glycoproteins.
Jon Ander Nieto-Garai +21 more
doaj +1 more source
Combining detection and reconstruction of correlational and quasi-periodic motifs in viral genomic sequences with transitional genome mapping: Application to COVID-19 [PDF]
Journal of Integrated OMICS, 2021, v.11(1) p.5-11, 2020 A method of Transitional Automorphic Mapping of the Genome on Itself (TAMGI) is aimed at combining detection and reconstruction of correlational and quasi-periodic motifs in the viral genomic RNA/DNA sequences. The motifs reconstructed by TAMGI are robust with respect to indels and point mutations and can be tried as putative therapeutic targets.
arxiv +1 more source
Tomato spotted wilt virus glycoproteins induce the formation of endoplasmic reticulum- and Golgi-derived pleomorphic membrane structures in plant cells [PDF]
, 2008 Tomato spotted wilt virus (TSWV) particles are spherical and enveloped, an uncommon feature among plant infecting viruses. Previous studies have shown that virus particle formation involves the enwrapment of ribonucleoproteins with viral glycoprotein ...
Denecke, J. +5 more
core +2 more sources
Platelet Membrane Glycoproteins: A Historical Review
Seminars in Thrombosis and Hemostasis, 2014 The search for the components of the platelet surface that mediate platelet adhesion and platelet aggregation began for earnest in the late 1960s when electron microscopy demonstrated the presence of a carbohydrate-rich, negatively charged outer coat ...
A. Nurden
semanticscholar +1 more source
Receptor-Targeted Nipah Virus Glycoproteins Improve Cell-Type Selective Gene Delivery and Reveal a Preference for Membrane-Proximal Cell Attachment. [PDF]
PLoS Pathogens, 2016 Receptor-targeted lentiviral vectors (LVs) can be an effective tool for selective transfer of genes into distinct cell types of choice. Moreover, they can be used to determine the molecular properties that cell surface proteins must fulfill to act as ...
Ruben R Bender +7 more
doaj +1 more source
Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity
Viruses, 2021 Host plasma membrane protein SERINC5 is incorporated into budding retrovirus particles where it blocks subsequent entry into susceptible target cells.
William E. Diehl +6 more
doaj +1 more source
A family of abundant plasma membrane-associated glycoproteins related to the arabinogalactan proteins is unique to flowering plants [PDF]
, 1989 We have identified a family of abundant peripheral plasma membrane glycoproteins that is unique to flowering plants. They are identified by a monoclonal antibody, MAC 207, that recognizes an epitope containing L-arabinose and D-glucuronic acid ...
Knox, JP +4 more
core +2 more sources
Scientific Reports, 2023 Tuberculosis (TB) remains one of the most afflictive bacterial infections globally. In high burden TB countries, surveillance, diagnosis and treatment of drug resistant TB (RR and X/MDRTB) display a crucial public health challenge. Therefore, we need new
Shamsi Yari +5 more
doaj +1 more source
Mechanisms of receptor/coreceptor-mediated entry of enveloped viruses [PDF]
Biophysical Journal, 96, 2624-2636, (2009), 2008 Enveloped viruses enter host cells either through endocytosis, or by direct fusion of the viral membrane envelope and the membrane of the host cell. However, some viruses, such as HIV-1, HSV-1, and Epstein-Barr can enter a cell through either mechanism, with the choice of pathway often a function of the ambient physical chemical conditions, such as ...
arxiv +1 more source
A natural ionic liquid: low molecular mass compounds of aggregate glue droplets on spider orb webs [PDF]
, 2022 The aggregate glue of spider orb web is an excellent natural adhesive. Orb-weaver spiders use micron-scale aggregate glue droplets to retain prey in the capture spiral silks of their orb web. In aggregate glue droplets, highly glycosylated and phosphorylated proteins dissolve in low molecular mass compounds.
arxiv +1 more source