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The Role of Osmolytes and Membrane Lipids in the Adaptation of Acidophilic Fungi [PDF]

open access: yesMicroorganisms, 2023
Acidophiles maintain near-neutral intracellular pH using proton pumps. We have suggested the protective role of osmolytes and membrane lipids in the adaptation to an acidic environment.
Elena A. Ianutsevich   +3 more
doaj   +2 more sources

Modulation of a rapid neurotransmitter receptor-ion channel by membrane lipids [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2023
Membrane lipids modulate the proteins embedded in the bilayer matrix by two non-exclusive mechanisms: direct or indirect. The latter comprise those effects mediated by the physicochemical state of the membrane bilayer, whereas direct modulation entails ...
Francisco J. Barrantes
doaj   +2 more sources

Characterization and Roles of Membrane Lipids in Fatty Liver Disease [PDF]

open access: yesMembranes, 2022
Obesity has reached global epidemic proportions and it affects the development of insulin resistance, type 2 diabetes, fatty liver disease and other metabolic diseases.
Morgan Welch   +9 more
doaj   +2 more sources

New Insights Into Targeting Membrane Lipids for Cancer Therapy

open access: yesFrontiers in Cell and Developmental Biology, 2020
Modulation of membrane lipid composition and organization is currently developing as an effective therapeutic strategy against a wide range of diseases, including cancer.
Giulio Preta
doaj   +2 more sources

Head-Group Acylation of Chloroplast Membrane Lipids [PDF]

open access: yesMolecules, 2021
Head group-acylated chloroplast lipids were discovered in the 1960s, but interest was renewed about 15 years ago with the discovery of Arabidopsides E and G, acylated monogalactosyldiacylglycerols with oxidized fatty acyl chains originally identified in ...
Yu Song   +3 more
doaj   +2 more sources

Biosynthesis of archaeal membrane ether lipids

open access: yesFrontiers in Microbiology, 2014
A vital function of the cell membrane in all living organism is to maintain the membrane permeability barrier and fluidity. The composition of the phospholipid bilayer is distinct in archaea when compared to bacteria and eukarya.
Samta eJain   +3 more
doaj   +2 more sources

Impaired membrane lipids in ischemic stroke: a key player in inflammation and thrombosis [PDF]

open access: yesJournal of Neuroinflammation
Background Membrane lipids play a crucial role in brain function and cell signalling, and they serve as key biological substrates in inflammatory responses, thrombosis, and energy metabolism.
Qian Wang   +14 more
doaj   +2 more sources

Cryo-EM structures of a protein pore reveal a cluster of cholesterol molecules and diverse roles of membrane lipids [PDF]

open access: yesNature Communications
The structure and function of membrane proteins depend on their interactions with lipids that constitute membranes. Actinoporins are α-pore-forming proteins that bind preferentially to sphingomyelin-containing membranes, where they oligomerize and form ...
Gašper Šolinc   +6 more
doaj   +2 more sources

Membrane lipids: where they are and how they behave

open access: yesNature Reviews Molecular Cell Biology, 2008
G. Meer, D. Voelker, G. Feigenson
exaly   +2 more sources

Emerging roles of ATG proteins and membrane lipids in autophagosome formation

open access: yesCell Discovery, 2020
Autophagosome biogenesis is a dynamic membrane event, which is executed by the sequential function of autophagy-related (ATG) proteins. Upon autophagy induction, a cup-shaped membrane structure appears in the cytoplasm, then elongates sequestering ...
Taki Nishimura, S. Tooze
semanticscholar   +2 more sources

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