Results 41 to 50 of about 433,130 (308)

Solubilization of lipids and lipid phases by the styrene-maleic acid copolymer [PDF]

, 2017
A promising tool in membrane research is the use of the styrene-maleic acid (SMA) copolymer to solubilize membranes in the form of nanodiscs. Since membranes are heterogeneous in composition, it is important to know whether SMA thereby has a preference ...
Dominguez Pardo, J.J., Dörr, J.M., Scheidelaar, S., Koorengevel, M.C., Cox, Ruud C, Iyer, A. (Aditya), Scheidelaar, Stefan, Membrane Biochemistry and Biophysics, Dörr, Jonas M, Iyer, Aditya, Dominguez Pardo, Juan J, Cox, R.C., Sub Membrane Biochemistry & Biophysics, Killian, J Antoinette, Subramaniam, Vinod, Koorengevel, Martijn C, Subramaniam, V. (Vinod), Killian, J.A.   +17 more
core   +1 more source

Modeling and Simulation of Lipid Membranes

Membranes, 2022
Cell membranes separate the interior of cells and the exterior environment, providing protection, controlling the passage of substances, and governing the interaction with other biomolecules and signalling processes [...]
Jordi Martí, Carles Calero
openaire   +7 more sources

Plasma membrane compartmentation in Saccharomyces cerevisiae

, 2009
In the plasma membrane of cells the complex variety of components is sorted into subcompartments, microdomains and nanoclusters. We only begin to understand the principles of this higher order.
Großmann, Guido
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Lipid bilayer composition influences small multidrug transporters

, 2008
Background: Membrane proteins are influenced by their surrounding lipids. We investigate the effect of bilayer composition on the membrane transport activity of two members of the small multidrug resistance family; the Escherichia coli transporter, EmrE
Charalambous, K, Curnow, Paul, Curnow, P., Curnow, P, Miller, D, Charalambous, Kalypso, Booth, Paula J, Miller, D., Booth, P.J., Miller, David, Booth, PJ   +10 more
core   +1 more source

Cell-free protein synthesis of membrane (1,3)-beta-D-glucan (curdlan) synthase: Co-translational insertion in liposomes and reconstitution in nanodiscs [PDF]

, 2013
A membrane-embedded curdlan synthase (CrdS) from Agrobacterium is believed to catalyse a repetitive addition of glucosyl residues from UDP-glucose to produce the (1,3)-β-d-glucan (curdlan) polymer.
Mertens, Haydyn D.T., Garajová, Soňa, Hrmova, Maria, Garajova, S., Hrmova, M., Mertens, H., Waters, Shane, Amalraj, Amritha, Nagarajan, Yagnesh, Nagarajan, Y., Waters, S., Periasamy, Agalya, Shadiac, N., Periasamy, A., Shadiac, Nadim, Amalraj, A.   +15 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The use of SMALPs as a novel membrane protein scaffold for structure study by negative stain electron microscopy. [PDF]

, 2015
Despite the great progress recently made in resolving their structures, investigation of the structural biology of membrane proteins still presents major challenges.
Shaun Rawson, Mitchell, JK, Postis, Vincent; id_orcid, Vincent Postis, Tim R Dafforn, Postis, Vincent, Muench, Stephen P., Baldwin, SA, Rawson, Shaun, Baldwin, Stephen A., Postis, V, Rawson, S, Stephen A Baldwin, Lee, SC, Rosemary A Parslow, Mitchell, Jennifer K., Dafforn, TR, Lee, Sarah C., Parslow, Rosemary A., Jennifer K Mitchell, Sarah C Lee, Stephen P Muench, Muench, SP, Dafforn, Tim R., Parslow, RA   +24 more
core   +1 more source

Submergence induced changes of molecular species in membrane lipids in Arabidopsis thaliana

Plant Diversity, 2016
The composition of membrane lipids is sensitive to environmental stresses. Submergence is a type of stress often encountered by plants. However, how the molecular species of membrane lipids respond to submergence has not yet been characterised.
Mulan Wang, Yunmei Shen, Faqing Tao, Shengchao Yang, Weiqi Li   +4 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source