Cell-free protein synthesis of membrane (1,3)-beta-D-glucan (curdlan) synthase: Co-translational insertion in liposomes and reconstitution in nanodiscs [PDF]
, 2013 A membrane-embedded curdlan synthase (CrdS) from Agrobacterium is believed to catalyse a repetitive addition of glucosyl residues from UDP-glucose to produce the (1,3)-β-d-glucan (curdlan) polymer.
Mertens, Haydyn D.T. +15 more
core +1 more source
Insights into membrane solubilization by styrene-maleic acid copolymers [PDF]
, 2018 Styrene-and-maleic acid copolymers (SMA) are gaining interest in membrane protein research due to their ability of solubilizing lipid membranes into nanodiscs.
Dominguez Pardo, J.J. +2 more
core
The use of SMALPs as a novel membrane protein scaffold for structure study by negative stain electron microscopy. [PDF]
, 2015 Despite the great progress recently made in resolving their structures, investigation of the structural biology of membrane proteins still presents major challenges.
Shaun Rawson +24 more
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Solubilization of lipids and membrane proteins into nanodiscs: Mode of action and applications of SMA copolymers [PDF]
, 2016 Cell membranes separate the inside and outside of cells. Membrane proteins in the cell membrane control the traffic of molecules across the membrane and are therefore targets for a lot of drugs: about 50 % of all approved drugs target a membrane protein!
Scheidelaar, S. +2 more
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Stability and membrane orientation of the fukutin transmembrane domain: a combined multiscale molecular dynamics and circular dichroism study [PDF]
, 2010 The N-terminal domain of Fukutin-I has been implicated in the localization of the protein in the endoplasmic reticulum/Golgi apparatus. It has been proposed to mediate this through its interaction with the thinner lipid bilayers found in these ...
Khalid, Syma +11 more
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Charged Lipids Influence Phase Separation in Cell-Sized Liposomes Containing Cholesterol or Ergosterol [PDF]
, 2022 Positively charged ion species and charged lipids play specific roles in biochemical processes, especially those involving cell membranes. The cell membrane and phase separation domains are attractive research targets to study signal transduction.
Tsuyoshi Yoda, Yoda, Tsuyoshi
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Submergence induced changes of molecular species in membrane lipids in Arabidopsis thaliana
Plant Diversity, 2016 The composition of membrane lipids is sensitive to environmental stresses. Submergence is a type of stress often encountered by plants. However, how the molecular species of membrane lipids respond to submergence has not yet been characterised.
Mulan Wang +4 more
doaj +1 more source
Protein-lipid interactions: paparazzi hunting for snap-shots [PDF]
, 2009 Photoactivatable groups meeting the criterion of minimal perturbance allow the investigation of interactions in biological samples. Here, we review the application of photoactivatable groups in lipids enabling the study of protein-lipid interactions in ...
Sub Membrane Enzymology begr. 01-06-12 +3 more
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Science and Technology of Advanced Materials, 2016 We studied real-time interaction between poly(ethylene glycol)-conjugated phospholipids (PEG-lipids) and a supported lipid membrane by surface plasmon resonance (SPR) spectroscopy to understand dynamic behaviors of PEG-lipids on living cell membranes ...
Toshihiro Yamamoto +4 more
doaj +1 more source
Biosynthesis of archaeal membrane ether lipids
Frontiers in Microbiology, 2014 A vital function of the cell membrane in all living organism is to maintain the membrane permeability barrier and fluidity. The composition of the phospholipid bilayer is distinct in archaea when compared to bacteria and eukarya.
Samta eJain +3 more
doaj +1 more source