Results 21 to 30 of about 265,407 (60)
The role of interfacial lipids in stabilizing membrane protein oligomers [PDF]
Oligomerization of membrane proteins in response to lipid binding has a critical role in many cell-signalling pathways1 but is often difficult to define2 or predict3.
A Anderluh+64 more
core +1 more source
Analytical derivation of thermodynamic properties of bolalipid membrane
We consider a model of bilayer lipid membrane with bola-lipids. The bola-lipid is modeled by linking tails of the hydrophobic chains in the opposite monolayers within bilayer as a first approximation.
Kheyfets, Boris B., Mukhin, Sergei I.
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Lipid profile of Xylella fastidiosa Subsp. pauca associated with the olive quick decline syndrome [PDF]
Lipids, components of the plasma and intracellular membranes as well as of droplets, provide different biological functions related to energy, carbon storage, and stress responses.
Manuel Salustri+6 more
core +2 more sources
Charge-induced phase separation in lipid membranes [PDF]
The phase separation in lipid bilayers that include negatively charged lipids is examined experimentally. We observed phase-separated structures and determined the membrane miscibility temperatures in several binary and ternary lipid mixtures of ...
Andelman, David+5 more
core +2 more sources
Electrostatic forces on charged surfaces of bilayer lipid membranes [PDF]
Simulating protein-membrane interactions is an important and dynamic area of research. A proper definition of electrostatic forces on membrane surfaces is necessary for developing electromechanical models of protein-membrane interactions. Here we modeled
Mikucki, Michael, Zhou, Y. C.
core
In eukaryotic cells, the trans-Golgi network (TGN) serves as a platform for secretory cargo sorting and trafficking. In recent years, it has become evident that a complex network of lipid-lipid and lipid-protein interactions contributes to these key ...
Hausser, A., von Blume, J.
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Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24. [PDF]
Off-target binding of hydrophobic drugs can lead to unwanted side effects, either through specific or non-specific binding to unintended membrane protein targets.
Carpenter, Elisabeth P+7 more
core +2 more sources
Flexible Lipid Bilayers in Implicit Solvent
A minimalist simulation model for lipid bilayers is presented. Each lipid is represented by a flexible chain of beads in implicit solvent. The hydrophobic effect is mimicked through an intermolecular pair potential localized at the ``water''/hydrocarbon ...
A. Ben-Shaul+14 more
core +1 more source
Membrane traffic: Cycling lipids [PDF]
When synaptic vesicles fuse with the presynaptic plasma membrane, their membrane constituents are recycled by internalisation into clathrin-coated vesicles.
Stenmark, Harald
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Hydrodynamics of Diffusion in Lipid Membrane Simulations
By performing molecular dynamics simulations with up to 132 million coarse-grained particles in half-micron sized boxes, we show that hydrodynamics quantitatively explains the finite-size effects on diffusion of lipids, proteins, and carbon nanotubes in ...
Hummer, Gerhard+2 more
core +1 more source