Results 151 to 160 of about 2,473,220 (258)

EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier

The FEBS Journal, EarlyView.
Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto, Gergő Porkoláb, Natalie Hudson, Jeffrey O'Callaghan, Nicole Hanley, Conor Delaney, Mária A. Deli, Peter Westenskow, Matthew Campbell   +8 more
wiley   +1 more source

Electron microscopy‐based three‐dimensional subcellular imaging of plant male gametophyte

Journal of Integrative Plant Biology, EarlyView.
The Aquilos2 Cryo‐FIB workflows provide practical routes for cryo‐electron tomography and volume imaging in plant structural biology. ABSTRACT Understanding cellular events in three dimensions (3D) is of great importance for the annotation and illustration of biological processes in a contextual way. Imaging techniques based on electron microscopy (EM),
Zhiqi Liu, Zizhen Liang, Mengfei Liao, Yixin Huang, Rui Ma, Jiayang Gao, Weiqi Wang, Tao Ni, Philipp S. Erdmann, Liwen Jiang   +9 more
wiley   +1 more source

Dehydration‐driven organization of metabolites into NaDES‐like assemblies in orthodox seeds

New Phytologist, EarlyView.
Summary Desiccation tolerance in plants, especially during orthodox seed dehydration, relies on compatible solute accumulation, complex molecular mechanisms, and intermolecular organizations that remain poorly understood. We combined metabolite profiling, mass spectrometry imaging, and electrospray and cold‐spray ionization mass spectrometry to ...
Youcef Haddad, Thomas Delhaye, Emmanuelle Limanton, Denis Morineau, Maëna Le Corvec, Christine Deponge, Anne Levrel, Alain Moréac, Virginie Nazabal, David Rondeau, Ludovic Paquin, Alain Bouchereau   +11 more
wiley   +1 more source

CryoEM architecture of a native stretch-sensitive membrane microdomain

, 2023
Kefauver JM, Hakala M, Zou L, Alba J, Espadas J, Tettamanti MG, Estrozi LF, Vanni S, Roux A, Desfosses A, Loewith R.   +10 more
europepmc   +1 more source

A Highly Conserved SNARE‐Associated Protein Enhances Plant Immunity by Regulating Vesicle Trafficking

Plant Biotechnology Journal, EarlyView.
ABSTRACT The plant endomembrane system and vesicle trafficking are central to plant immunity, mediating the targeted delivery and recycling of defence molecules during pathogen attack. Here, we investigated the functional role of soybean Vacuole Membrane Protein 1 (GmVMP1) in mediating resistance against soybean cyst nematode (SCN, Heterodera glycines).
Tracy E. Hawk, Peitong Li, Hafiz Muhammad Khalid Abbas, Mst Shamira Sultana, Sarbottam Piya, Nicole Coffey, Cengizhan Öztürk, Sobhan Bahrami Zadegan, Susan Thomas Laird, Mazen Alazem, Samantha P. Nuzzi, J. Hollis Rice, Chris Wyman, Tessa Burch‐Smith, Vince Pantalone, Tarek Hewezi   +15 more
wiley   +1 more source

Inhibition of K-Ras4B-plasma membrane association with a membrane microdomain-targeting peptide. [PDF]

Chem Sci, 2019
Li FY, Zhang ZF, Voss S, Wu YW, Zhao YF, Li YM, Chen YX.   +6 more
europepmc   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Spherulite in the modern aragonitic travertine stromatolite has a calcite core with exopolymers

Sedimentology, EarlyView.
ABSTRACT Spherulites are spherical to ellipsoidal particles formed by various crystalline substances and can be abiotically synthesised in the laboratory. Among various spherulite types, spherulites composed of calcium carbonate are also found in various natural environments, but their abiotic or biotic origins are still controversial.
Fumito Shiraishi, Takayuki Akimoto, Naotaka Tomioka, Satoko Motai, Yoshio Takahashi   +4 more
wiley   +1 more source

Brij detergents reveal new aspects of membrane microdomain in erythrocytes

Molecular membrane biology, 2014
B. R. Casadei, Patrícia de Oliveira Carvalho, K. Riske, R. Barbosa, E. de Paula, C. Domingues   +5 more
semanticscholar   +1 more source

Structure mirroring function: What's the ‘matter’ with the funny current?

The Journal of Physiology, EarlyView.
Abstract figure legend The ‘funny’ (If) current of cardiac pacemaker cells has been first identified in the late 1970s as a major mechanism in the generation and control of cardiac pacemaking. Decades of studies have since described the properties of the funny current and of its molecular components, HCN channels, in the heart and brain, providing the ...
Andrea Saponaro, Dario DiFrancesco
wiley   +1 more source