Results 201 to 210 of about 2,473,220 (258)

Advances in astrocytic calcium signaling research. [PDF]

Front Cell Neurosci
Chen Y, Ye Y, Jia J, Long B, Dou T, Yan X.   +5 more
europepmc   +1 more source

The endoplasmic reticulum in mitochondrial protein targeting: A neuronal perspective on organelle crosstalk

Protein Science, Volume 35, Issue 3, March 2026.
Abstract Neurons depend on tightly regulated spatial proteostasis to maintain function across their extended morphology. The endoplasmic reticulum (ER), traditionally known for its function in protein synthesis, folding, and trafficking, has long been recognized as a central platform for directing proteins to organelles of the secretory and endocytic ...
J. Tabitha Hees, Angelika B. Harbauer
wiley   +1 more source

Designing AI-generated antimicrobials for targeting bacterial microdomains. [PDF]

Sci Rep
Rzycki M, Gruda A.
europepmc   +1 more source

Insights into the roles of RALF peptides and CrRLK1L receptors in fruit ripening

The Plant Journal, Volume 125, Issue 5, March 2026.
SUMMARY The rapid alkalinization factor (RALF) family of small signaling peptides regulates diverse physiological and developmental processes in plants. RALF peptides influence cell wall remodeling and hormonal homeostasis through interactions with CrRLK1L malectin‐like receptor kinases and leucine‐rich repeat extensin (LRX) proteins anchored to the ...
José A. Montano, Sara Posé, José A. Mercado, Verónica G. Doblas   +3 more
wiley   +1 more source

Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions

Traffic, Volume 27, Issue 1, March 2026.
Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule‐dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential physiological functions such as plasma membrane repair, maintenance of cellular homeostasis, and participation in signal transduction.
Shanshan Jiang, Jingyi Fu, Shan Li, Zehui Li, Qirui Zhao, Yuqi Yin, Mei Yang, Yonghua Wang   +7 more
wiley   +1 more source

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1. [PDF]

FEBS Lett
Nakatsuji T, Shiraishi K, Wang C, Yurimoto H, Sakai Y, Oku M.   +5 more
europepmc   +1 more source

Optimal neuromuscular performance requires motor neuron phosphagen kinases

The Journal of Physiology, Volume 604, Issue 5, Page 2027-2059, 1 March 2026.
Abstract figure legend Motor neuron (MN) terminals in fruit flies, mice and humans contain phosphagen kinases, a key enzyme in their energy storage and buffering system. Here we knocked down the primary phosphagen kinase in fruit fly larvae (arginine kinase 1 (ArgK1)) but were surprised to find that MN endurance was unaffected.
Karlis A. Justs, Danielle V. Latner (nee Riboul), Carlos D. Oliva, Yosuf Arab, Gabriel G. Bonassi, Olena Mahneva, Sarah Crill, Sergio Sempertegui, Paul A. Kirchman, Yaouen Fily, Gregory T. Macleod   +10 more
wiley   +1 more source

Tetraspanins: Small transmembrane proteins with big impact on membrane microdomain structures. [PDF]

Commun Integr Biol, 2008
Singethan K, Schneider-Schaulies J.
europepmc   +1 more source

Aging‐Driven Inter‐Organ Crosstalk in Postmenopausal Osteoporosis: From Immunometabolic Drift to Multisystem Frailty

The FASEB Journal, Volume 40, Issue 4, 28 February 2026.
Postmenopausal osteoporosis (PMOP) is increasingly recognized as an aging‐associated, multisystem state of fragility, in which estrogen deficiency exacerbates immune and metabolic drift across the bone marrow, skeletal muscle, adipose tissue, gut, vascular system, and neural circuits.
Xianlin Rao, Xiaoyu Cai
wiley   +1 more source

Membrane Dysfunction as a Central Mechanism in LRRK2-Associated Parkinson's Disease: Comparative Analysis of G2019S and I1371V Variants. [PDF]

Cells
Singh K, Banerjee R, Potdar C, Shaw A, Rakshith R, Kamble N, Holla V, Yadav R, Pal PK, Datta I.   +9 more
europepmc   +1 more source