Results 1 to 10 of about 628,659 (381)

Statistical Mechanics of Membrane Protein Conformation: A Homopolymer Model [PDF]

Phys. Rev. Lett. 80, 5687 (1998), 1998
The conformation and the phase diagram of a membrane protein are investigated via grand canonical ensemble approach using a homopolymer model. We discuss the nature and pathway of $\alpha$-helix integration into the membrane that results depending upon membrane permeability and polymer adsorptivity.
A. Baumgärtner, A. M. Gutin, B. H. Zimm, C. Branden, D. F. H. Wallach, D. K. Klimov, D. Poland, E. A. DiMarzio, E. Eisenriegler, F. W. Wiegel, I. M. Lifshitz, J. K. Myers, J. Lenard, J. Wang, J.-L. Popot, K. S. J. Nordholm, M. A. Lemmon, M. A. Lemmon, M. Ueda, P. D. Ross, P. G. Wolynes, P. J. Park, Pyeong Jun Park, R. E. Jacobs, R. Henderson, R. Lipowsky, T. Garel, V. S. Pande, W. Sung, W. Sung   +29 more
arxiv   +4 more sources

Cyclic peptide membrane permeability prediction using deep learning model based on molecular attention transformer [PDF]

Frontiers in Bioinformatics
Membrane permeability is a critical bottleneck in the development of cyclic peptide drugs. Experimental membrane permeability testing is costly, and precise in silico prediction tools are scarce.
Dawei Jiang, Zixi Chen, Zixi Chen, Hongli Du   +3 more
doaj   +2 more sources

ULTRASTRUCTURE AND PERMEABILITY OF NUCLEAR MEMBRANES [PDF]

The Journal of Cell Biology, 1965
The fine structures of nuclear envelopes known to have different permeability properties were compared. Membranes of salivary gland cell nuclei of Drosophila (third instar) and Chironomus (prepupae), which are strong barriers to ion diffusion, and membranes of oocyte nuclei (germinal vesicle) of Xenopus and Triturus, which are much more ion-permeable ...
Joseph Wiener, David Spiro, Werner R. Loewenstein   +2 more
openalex   +4 more sources

Analysis of Antimicrobial-Triggered Membrane Depolarisation Using Voltage Sensitive Dyes [PDF]

Frontiers in Cell and Developmental Biology, 2016
The bacterial cytoplasmic membrane is a major inhibitory target for antimicrobial compounds. Commonly, although not exclusively, these compounds unfold their antimicrobial activity by disrupting the essential barrier function of the cell membrane.
J. Derk te Winkel, Declan A. Gray, Kenneth H. Seistrup, Leendert W. Hamoen, Henrik eStrahl   +4 more
doaj   +5 more sources

CO2 permeability of the rat erythrocyte membrane and its inhibition

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
We have studied the CO2 permeability of the erythrocyte membrane of the rat using a mass spectrometric method that employs 18 O-labelled CO2. The method yields, in addition, the intraerythrocytic carbonic anhydrase activity and the membrane HCO3 ...
Samer Al-Samir, Maximilian Prill, Claudiu T. Supuran, Gerolf Gros, Volker Endeward   +4 more
doaj   +1 more source

Alpha-toxin induces programmed cell death of human T cells, B cells, and monocytes during USA300 infection. [PDF]

PLoS ONE, 2012
This investigation examines the influence of alpha-toxin (Hla) during USA300 infection of human leukocytes. Survival of an USA300 isogenic deletion mutant of hla (USA300Δhla) in human blood was comparable to the parental wild-type strain and ...
Tyler K Nygaard, Kyler B Pallister, Ashley L DuMont, Mark DeWald, Robert L Watkins, Erik Q Pallister, Cheryl Malone, Shannon Griffith, Alexander R Horswill, Victor J Torres, Jovanka M Voyich   +10 more
doaj   +1 more source

Amide-to-ester substitution as a stable alternative to N-methylation for increasing membrane permeability in cyclic peptides

Nature Communications, 2023
Naturally occurring peptides with high membrane permeability often have backbone ester bonds. Here, the authors investigated the effect of an amide-to-ester substitution on membrane permeability of peptides and found the substitution is useful for ...
Yuki Hosono, Satoshi Uchida, Moe Shinkai, Chad E. Townsend, Colin N. Kelly, Matthew R. Naylor, Hsiau-Wei Lee, Kayoko Kanamitsu, Mayumi Ishii, Ryosuke Ueki, Takumi Ueda, Koh Takeuchi, Masatake Sugita, Yutaka Akiyama, Scott R. Lokey, Jumpei Morimoto, Shinsuke Sando   +16 more
doaj   +1 more source

Fabrication and Characterization of Chitosan/N-Phthaloyl Composite Membrane for DMFC Application

Jurnal Riset Kimia, 2021
Modified chitosan membrane is one of the promising membranes for polymer electrolyte membrane. Chitosan/N-phthaloyl chitosan composite membranes were fabricated to obtain high proton conductivity and low methanol permeability.
Christine Dyta Nugraeni, Lukman Atmaja, Nur Hayati, Mochammad Purwanto, Mardi Santoso, Yuli Kusumawati   +5 more
doaj   +1 more source

Study of effective parameters on the transport of dysprosium through a supported liquid membrane containing Cyanex 272 as a carrier [PDF]

مجله علوم و فنون هسته‌ای, 2022
In this study, the extraction of dysprosium was investigated using a supported liquid membrane (SLM) system. The experiments were performed using bis (2, 4, and 4-trimethylpentyl) phosphinic acid (Cyanex272) as the carrier.
F. Zahakifar, P. Zaheri, M. Ghanadi Maragheh   +2 more
doaj   +1 more source

Fabrication of a Novel (PVDF/MWCNT/Polypyrrole) Antifouling High Flux Ultrafiltration Membrane for Crude Oil Wastewater Treatment

Membranes, 2022
The present work deals with the fabrication of novel poly(vinylidene fluoride) (PVDF)/Multi-wall Carbon Nanotubes (MWCNT)/Polypyrrole (PPy) ultrafiltration membrane by phase inversion technique for the removal of crude oil from refinery wastewater.
Banan Hudaib, Rund Abu-Zurayk, Haneen Waleed, Abed Alqader Ibrahim   +3 more
doaj   +1 more source