Results 71 to 80 of about 1,747,226 (292)

MultiCycPermea: accurate and interpretable prediction of cyclic peptide permeability using a multimodal image-sequence model

BMC Biology
Background Cyclic peptides, known for their high binding affinity and low toxicity, show potential as innovative drugs for targeting “undruggable” proteins. However, their therapeutic efficacy is often hindered by poor membrane permeability.
Zixu Wang, Yangyang Chen, Yifan Shang, Xiulong Yang, Wenqiong Pan, Xiucai Ye, Tetsuya Sakurai, Xiangxiang Zeng   +7 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Differential Behavior of Salt and Organic Matter Passage in 2-Pass RO Systems for Ultrapure Water Production

Separations
This study investigates how membrane transport characteristics affect permeate quality in a 2-pass reverse osmosis (RO) system for ultrapure water (UPW) production. Unlike conventional RO, UPW-RO operates in an ultra-low concentration range.
Changryeol Oh, Dongkeon Kim, Suhan Kim
doaj   +1 more source

CO2 Permeability of Biological Membranes and Role of CO2 Channels

Membranes, 2017
We summarize here, mainly for mammalian systems, the present knowledge of (a) the membrane CO2 permeabilities in various tissues; (b) the physiological significance of the value of the CO2 permeability; (c) the mechanisms by which membrane CO2 ...
Volker Endeward, Mariela Arias-Hidalgo, Samer Al-Samir, Gerolf Gros   +3 more
doaj   +1 more source

Characterization and evaluation of carbon nanotube Bucky-Paper membranes for direct contact membrane distillation [PDF]

, 2010
Self-supporting carbon nanotube (CNT) Bucky-Papers have unique structural and surface properties which can be utilised in many applications. In this work we characterised pure self-supporting CNT membranes, where CNTs were held together only by Van der ...
Sears, Kallista, Schutz, Jurg, Finn, Niall, Huynh, Chi, Hawkins, Stephen, Gray, Stephen, Duke, Mikel, Dumee, Ludovic, Gray, Stephen R   +8 more
core   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

CORRELATION BETWEEN POLYMER PACKING AND GAS TRANSPORT PROPERTIES FOR CO2/N2 SEPARATION IN GLASSY FLUORINATED POLYIMIDE MEMBRANE [PDF]

Journal of Engineering Science and Technology, 2016
Gas separation performance of a membrane highly hinges on its physical properties. In this study, the interplay between polymer packing of a membrane and its gas transport behaviours (permeability and selectivity) was investigated through a series of ...
P. C. TAN, Z. A. JAWAD, B. S. OOI, A. L. AHMAD, S. C. LOW   +4 more
doaj  

Physiological adaptation of invasive plant Erigeron philadelphicus to different environments

浙江大学学报. 农业与生命科学版, 2008
Erigeron philadelphicus is a new plant invader in the suburb of Shanghai. In order to understand better its physiological adaptability to different stresses, the relative membrane permeability, the concentrations of malonaldehyde (MDA), free proline ...
HU Tian-yin, WANG Yong, YIN Li-ping, GUO Shui-liang   +3 more
doaj   +1 more source