Results 31 to 40 of about 3,436,061 (328)

Membrane Potential Assessment by Fluorimetry as a Predictor Tool of Human Sperm Fertilizing Capacity

Frontiers in Cell and Developmental Biology, 2020
Mammalian sperm acquire the ability to fertilize eggs by undergoing a process known as capacitation. Capacitation is triggered as the sperm travels through the female reproductive tract.
Carolina Baro Graf, Carolina Baro Graf, Carla Ritagliati, Valentina Torres-Monserrat, Cintia Stival, Carlos Carizza, Mariano G. Buffone, Dario Krapf, Dario Krapf   +8 more
doaj   +1 more source

Anoxic spreading depolarization in the neonatal rat cortex in vitro

Frontiers in Cellular Neuroscience, 2023
Anoxic spreading depolarization (aSD) is a hallmark of ischemic injury in the cerebral cortex. In adults, aSD is associated with rapid and nearly complete neuronal depolarization and loss of neuronal functions.
Azat Gainutdinov, Azat Gainutdinov, Elvira Juzekaeva, Marat Mukhtarov, Roustem Khazipov, Roustem Khazipov   +5 more
doaj   +1 more source

Relocation of active site carboxylates in major facilitator superfamily multidrug transporter LmrP reveals plasticity in proton interactions [PDF]

, 2016
The expression of polyspecific membrane transporters is one important mechanism by which cells can obtain resistance to structurally different antibiotics and cytotoxic agents.

core   +2 more sources

ASCs-Exosomes Recover Coupling Efficiency and Mitochondrial Membrane Potential in an in vitro Model of ALS

Frontiers in Neuroscience, 2019
The amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by motoneurons death. Mutations in the superoxide dismutase 1 (SOD1) protein have been identified to be related to the disease.
Elisa Calabria, Ilaria Scambi, Roberta Bonafede, Lorenzo Schiaffino, Daniele Peroni, Valentina Potrich, Carlo Capelli, Carlo Capelli, Federico Schena, Raffaella Mariotti   +9 more
doaj   +1 more source

Evaluation of the Anticancer Properties of Geranyl Isovalerate, an Active Ingredient of Argyreia nervosa Extract in Colorectal Cancer Cells

Frontiers in Pharmacology, 2021
Chemotherapy is a general treatment procedure for cancer. The diversity in cancer incidence and the failure of therapy due to chemoresistance lead to increased cancer-related deaths.
Fayyaz Rasool, Deepu Sharma, P. Shanmukha Anand, SKJ Magani, Srinivasan Tantravahi   +4 more
doaj   +1 more source

Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure. [PDF]

, 2012
Inflammation enhances the secretion of sphingomyelinases (SMases). SMases catalyze the hydrolysis of sphingomyelin into phosphocholine and ceramide.
Bosman, GJ, Brock, R, Cluitmans, JC, Dinkla, S, Fransen, J, Fuchs, B, Joosten, I, Schiller, J, Tomelleri, C, Verdurmen, WP, Wessels, K   +10 more
core   +1 more source

Stochastic Dynamics of Electrical Membrane with Voltage-Dependent Ion Channel Fluctuations

, 2014
Brownian ratchet like stochastic theory for the electrochemical membrane system of Hodgkin-Huxley (HH) is developed. The system is characterized by a continuous variable $Q_m(t)$, representing mobile membrane charge density, and a discrete variable $K_t$
Qian, Hong, Qian, Min, Zhang, Xue-Juan
core   +1 more source

Determination of a Robust Assay for Human Sperm Membrane Potential Analysis

Frontiers in Cell and Developmental Biology, 2019
Mammalian sperm must undergo a complex process called capacitation in order to fertilize the egg. During this process, hyperpolarization of the sperm plasma membrane has been mostly studied in mouse, and associated to its importance in the preparation to
Carolina Baro Graf, Carolina Baro Graf, Carla Ritagliati, Cintia Stival, Paula A. Balestrini, Mariano G. Buffone, Darío Krapf, Darío Krapf   +7 more
doaj   +1 more source

MODULATION OF DEFENSIVE REFLEX CONDITIONING IN SNAILS BY SEROTONIN

Frontiers in Behavioral Neuroscience, 2015
We studied the role of serotonin in the mechanisms of learning in terrestrial snails. To produce a serotonin deficit, the neurotoxic analogues of serotonin, 5,6- or 5,7-dihydroxytryptamine (5,6/5,7-DHT) were used.
Vyatcheslav V Andrianov, Vyatcheslav V Andrianov, Tatiana Kh Bogodvid, Tatiana Kh Bogodvid, Irina B Deryabina, Aleksandra N Golovchenko, Lyudmila N Muranova, Roza R Tagirova, Alia Kh Vinarskaya, Khalil L Gainutdinov, Khalil L Gainutdinov   +10 more
doaj   +1 more source

Myography of isolated blood vessels: Considerations for experimental design and combination with supplementary techniques

Frontiers in Physiology, 2023
The study of the mechanisms of regulation of vascular tone is an urgent task of modern science, since diseases of the cardiovascular system remain the main cause of reduction in the quality of life and mortality of the population.
Rudolf Schubert, Dina Gaynullina, Anastasia Shvetsova, Olga S. Tarasova, Olga S. Tarasova   +4 more
doaj   +1 more source