Results 51 to 60 of about 17,774,292 (335)

Outer membrane protein A (OmpA) as a potential therapeutic target for Acinetobacter baumannii infection

open access: yesJournal of Biomedical Sciences, 2020
Acinetobacter baumannii (A. baumannii) is an important opportunistic pathogen causing serious nosocomial infections, which is considered as the most threatening Gram-negative bacteria (GNB).
D. Nie   +7 more
semanticscholar   +1 more source

MODULATION OF DEFENSIVE REFLEX CONDITIONING IN SNAILS BY SEROTONIN

open access: yesFrontiers in Behavioral Neuroscience, 2015
We studied the role of serotonin in the mechanisms of learning in terrestrial snails. To produce a serotonin deficit, the neurotoxic analogues of serotonin, 5,6- or 5,7-dihydroxytryptamine (5,6/5,7-DHT) were used.
Vyatcheslav V Andrianov   +10 more
doaj   +1 more source

Myography of isolated blood vessels: Considerations for experimental design and combination with supplementary techniques

open access: yesFrontiers in Physiology, 2023
The study of the mechanisms of regulation of vascular tone is an urgent task of modern science, since diseases of the cardiovascular system remain the main cause of reduction in the quality of life and mortality of the population.
Rudolf Schubert   +4 more
doaj   +1 more source

Modeling Interference-Free Neuron Spikes with Optogenetic Stimulation [PDF]

open access: yes, 2019
This paper predicts the ability to externally control the firing times of a cortical neuron whose behavior follows the Izhikevich neuron model. The Izhikevich neuron model provides an efficient and biologically plausible method to track a cortical neuron'
Eckford, Andrew W.   +3 more
core   +2 more sources

A low-voltage activated, transient calcium current is responsible for the time-dependent depolarizing inward rectification of rat neocortical neurons in vitro [PDF]

open access: yes, 1987
Intracellular recordings were obtained from rat neocortical neurons in vitro. The current-voltage-relationship of the neuronal membrane was investigated using current- and single-electrode-voltage-clamp techniques.
A Constanti   +37 more
core   +1 more source

Noradrenaline Modulates the Membrane Potential and Holding Current of Medial Prefrontal Cortex Pyramidal Neurons via β1-Adrenergic Receptors and HCN Channels

open access: yesFrontiers in Cellular Neuroscience, 2017
The medial prefrontal cortex (mPFC) receives dense noradrenergic projections from the locus coeruleus. Adrenergic innervation of mPFC pyramidal neurons plays an essential role in both physiology (control of memory formation, attention, working memory ...
Katarzyna Grzelka   +3 more
doaj   +1 more source

Relocation of active site carboxylates in major facilitator superfamily multidrug transporter LmrP reveals plasticity in proton interactions [PDF]

open access: yes, 2016
The expression of polyspecific membrane transporters is one important mechanism by which cells can obtain resistance to structurally different antibiotics and cytotoxic agents.

core   +2 more sources

Ion channels to inactivate neurons in Drosophila

open access: yesFrontiers in Molecular Neuroscience, 2009
Ion channels are the determinants of excitability; therefore, manipulation of their levels and properties provides an opportunity for the investigator to modulate neuronal and circuit function.
James J L Hodge
doaj   +1 more source

Joule heating involving ion currents through channel proteins

open access: yesBiophysics and Physicobiology, 2023
Ion currents associated with channel proteins in the presence of membrane potential are ubiquitous in cellular and organelle membranes. When an ion current occurs through a channel protein, Joule heating should occur. However, this Joule heating seems to
Tetsuichi Wazawa, Takeharu Nagai
doaj   +1 more source

Stochastic Dynamics of Electrical Membrane with Voltage-Dependent Ion Channel Fluctuations

open access: yes, 2014
Brownian ratchet like stochastic theory for the electrochemical membrane system of Hodgkin-Huxley (HH) is developed. The system is characterized by a continuous variable $Q_m(t)$, representing mobile membrane charge density, and a discrete variable $K_t$
Qian, Hong, Qian, Min, Zhang, Xue-Juan
core   +1 more source

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