Osteopontin enhances sperm capacitation and in vitro fertilization efficiency in boars [PDF]
Journal of Animal Science and Technology, 2022 In this study, we used more reliable experimental materials and methods to detect the effects of osteopontin (OPN) on boar sperm in vitro capacitation, acrosome reaction, and fertilization efficiency.
Yun Chen, Kai Wang, Shouquan Zhang
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A special perspective on human fertilization: The role of sperm capacitation proteins and channels: A narrative review [PDF]
International Journal of Reproductive BioMedicineSperm undergo a last step of maturation known as capacitation in the female reproductive system, which prepares themselves to fertilize the ovum. Mechanisms of capacitation include changes in membrane composition, electrolyte concentration, pH levels ...
Nasrin Malverdi +6 more
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Time to revise: impact of methodology on boar sperm capacitation in vitro via phosphotyrosine patterns [PDF]
BMC Veterinary ResearchCapacitation is a crucial sperm maturation process occurring in vivo in the female reproductive tract, enabling spermatozoa to fertilize the oocyte. In vitro, capacitation can be induced using defined capacitation media (CM), with further assessment of ...
Barbora Klusackova +8 more
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Cordycepin improves hyperactivation and acrosome reaction through adenosine receptors during human sperm capacitation in vitro [PDF]
Reproductive Biology and EndocrinologyBackground Sperm capacitation is a prerequisite for natural or in vitro fertilization. After capacitation, sperm become hyperactivated and undergo an acrosome reaction, which helps them penetrate the oocyte.
Lijun Shan +8 more
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Capacitation promotes a shift in energy metabolism in murine sperm
Frontiers in Cell and Developmental Biology, 2022 In mammals, sperm acquire fertilization ability after a series of physiological and biochemical changes, collectively known as capacitation, that occur inside the female reproductive tract. In addition to other requirements, sperm bioenergetic metabolism
Maximiliano Tourmente, Eduardo Rial
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Increased mitochondrial activity upon CatSper channel activation is required for mouse sperm capacitation [PDF]
Redox Biology, 2021 To fertilize an oocyte, sperm must undergo several biochemical and functional changes known as capacitation. A key event in capacitation is calcium influx through the cation channel of sperm (CatSper).
Juan J. Ferreira +8 more
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Quantitative phosphoproteomics analyses reveal the regulatory mechanisms related to frozen-thawed sperm capacitation and acrosome reaction in yak (Bos grunniens) [PDF]
Frontiers in Physiology, 2022 Mammalian spermatozoa are not mature after ejaculation and must undergo additional functional and structural changes within female reproductive tracts to achieve subsequent fertilization, including both capacitation and acrosome reaction (AR), which are ...
Renzheng Zhang +9 more
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New insights into posttranslational modifications of proteins during bull sperm capacitation [PDF]
Cell Communication and Signaling, 2023 Background Due to the unique nature of spermatozoa, which are transcriptionally and translationally silent, the regulation of capacitation is based on the formation of posttranslational modifications of proteins (PTMs).
Agnieszka Mostek-Majewska +3 more
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Bottom-up approach to deciphering the targets of the ubiquitin-proteasome system in porcine sperm capacitation [PDF]
Scientific ReportsCapacitation is an essential post-testicular maturation event endowing spermatozoa with fertilizing capacity within the female reproductive tract, significant for fertility, reproductive health, and contraception.
Michal Zigo +7 more
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Citrate Promotes Nitric Oxide Production during Human Sperm Capacitation [PDF]
AntioxidantsSperm capacitation is a complex process essential for the spermatozoon to recognize and fertilize the oocyte. For capacitation to occur, human spermatozoa require low levels of reactive oxygen species (ROS), increased protein tyrosine phosphorylation ...
Diego Loggia, Cristian O’Flaherty
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