Results 11 to 20 of about 134,084 (212)

Citrate Promotes Nitric Oxide Production during Human Sperm Capacitation [PDF]

open access: yesAntioxidants
Sperm capacitation is a complex process essential for the spermatozoon to recognize and fertilize the oocyte. For capacitation to occur, human spermatozoa require low levels of reactive oxygen species (ROS), increased protein tyrosine phosphorylation ...
Diego Loggia, Cristian O’Flaherty
doaj   +3 more sources

F4-Neuroprostanes: A Role in Sperm Capacitation. [PDF]

open access: yesLife (Basel), 2021
F4-neuroprostanes (F4-NeuroPs), derived from the oxidative metabolization of docosahexaenoic acid (DHA), are considered biomarkers of oxidative stress in neurodegenerative diseases. Neurons and spermatozoa display a high DHA content. NeuroPs might possess biological activities. The aim of this in vitro study was to investigate the biological effects of
Signorini C   +11 more
europepmc   +11 more sources

Bull Sperm Capacitation Is Accompanied by Redox Modifications of Proteins [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
The ability to fertilise an egg is acquired by the mammalian sperm during the complex biochemical process called capacitation. Capacitation is accompanied by the production of reactive oxygen species (ROS), but the mechanism of redox regulation during ...
Andrzej Ciereszko   +2 more
exaly   +3 more sources

Bioenergetics of Mammalian Sperm Capacitation [PDF]

open access: yesBioMed Research International, 2014
After ejaculation, the mammalian male gamete must undergo the capacitation process, which is a prerequisite for egg fertilization. The bioenergetics of sperm capacitation is poorly understood despite its fundamental role in sustaining the biochemical and molecular events occurring during gamete activation.
FERRAMOSCA, Alessandra, ZARA, Vincenzo
openaire   +5 more sources

Redox regulation of mammalian sperm capacitation

open access: yesAsian Journal of Andrology, 2015
Capacitation is a series of morphological and metabolic changes necessary for the spermatozoon to achieve fertilizing ability. One of the earlier happenings during mammalian sperm capacitation is the production of reactive oxygen species (ROS) that will ...
Cristian O′Flaherty
doaj   +2 more sources

Zinc ion flux during mammalian sperm capacitation

open access: yesNature Communications, 2018
During sperm capacitation physiological changes occur that are required for fertilization. Here, the authors describe four sperm zinc signatures during invitro capacitation that are indicative of sperm quality and capacity to fertilize.
Karl Kerns   +4 more
doaj   +2 more sources

Levels of Protein CoAlation Regulate Redox Signaling Events of Human Sperm Capacitation [PDF]

open access: yesAntioxidants
Infertility is a global health problem, with male factors contributing to nearly half of all cases. Up to 30% of male infertility is classified as idiopathic, in part because routine semen analysis does not assess sperm fertilizing competence ...
Chika Onochie   +3 more
doaj   +2 more sources

Capacitation induces changes in metabolic pathways supporting motility of epididymal and ejaculated sperm

open access: yesFrontiers in Cell and Developmental Biology, 2023
Mammalian sperm require sufficient energy to support motility and capacitation for successful fertilization. Previous studies cataloging the changes to metabolism in sperm explored ejaculated human sperm or dormant mouse sperm surgically extracted from ...
Pablo Visconti   +2 more
exaly   +3 more sources

Mammalian sperm capacitation: In vivo and in vitro juxtaposition [PDF]

open access: yesVeterinary Integrative Sciences, 2022
The development of assisted reproductive technologies (ART) in mammalian species such as in vitro embryo production (IVEP) has the potential to provide great benefits for significant population increase, improve genetic performance and ...
Haris Setiawan   +4 more
doaj   +2 more sources

Computational Modelling of Sperm Behaviour in a 3D Virtual Oviduct [PDF]

open access: yes, 2011
The processes by which individual sperm cells navigate the length and complexity of the female reproductive tract and then reach and fertilise the oocyte are fascinating. Numerous complex processes potentially influence the movement of spermatozoa within
Burkitt, Mark
core   +6 more sources

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