Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF [PDF]
, 2016 STUDY QUESTION. Are significant abnormalities in outward (K+) conductance and resting membrane potential (Vm) present in the spermatozoa of patients undertaking IVF and ICSI and if so, what is their functional effect on fertilization success?
Barratt, Christopher L. R. +9 more
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Inhibiting sperm pyruvate dehydrogenase complex and its E3 subunit, dihydrolipoamide dehydrogenase affects fertilization in Syrian hamsters. [PDF]
PLoS ONE, 2014 BACKGROUND/AIMS: The importance of sperm capacitation for mammalian fertilization has been confirmed in the present study via sperm metabolism.
Archana B Siva +5 more
doaj +1 more source
Functional characterization of the domains of the bovine binder of SPerm 5 (BSP5) protein [PDF]
, 2015 BACKGROUND: Bovine BSP5 is a multifunctional protein primarily involved in sperm capacitation. BSP5 consists of long N-terminal part followed by two similar and highly conserved fibronectin type II domains designated A and B.
Geneviève Plante +3 more
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Hormones and Sperm Capacitation in Rabbits
Experimental Biology and Medicine, 1971 SummaryBilaterally ovariectomized does were maintained on 1 μg of estradiol benzoate/kg of body wt/day and given various levels of either progesterone (P) or 20-α-hy-droxyprogesterone (20α-OHP) following mating to fertile bucks. Compared with estrogen-treated controls, a single injection of 0.5 and 1.0 mg of 20α-OHP and 0.15 mg of P increased the ...
E D, Plotka, W L, Williams
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BMC Genomics, 2018 Background Capacitation, a prerequisite for oocyte fertilization, is a complex process involving series of structural and functional changes in sperms such as membrane modifications, modulation of enzyme activities, and protein phosphorylation.
Yuan Li +10 more
doaj +1 more source
Dissociation between AKAP3 and PKARII promotes AKAP3 degradation in sperm capacitation. [PDF]
PLoS ONE, 2013 Ejaculated spermatozoa must undergo a series of biochemical modifications called capacitation, prior to fertilization. Protein-kinase A (PKA) mediates sperm capacitation, although its regulation is not fully understood.
Pnina Hillman +3 more
doaj +1 more source
Effect of estrogens on boar sperm capacitation
Reproductive Biology and Endocrinology, 2010 Background Mammalian sperm must undergo a series of controlled molecular processes in the female reproductive tract called capacitation before they are capable of penetrating and fertilizing the egg.
Ded Lukas +4 more
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Development of a biomolecular approach to identify sperm functions and fertility using sperm RNAs
Frontiers in Cell and Developmental Biology, 2023 Infertility affects a significant percentage of couples worldwide, and male factors contribute significantly to this problem. Traditional assessments of male fertility rely primarily on parameters such as sperm motility, morphology, viability, and ...
Won-Ki Pang +2 more
doaj +1 more source
Protein-carbohydrate interactions during fertilization [PDF]
, 1998 Interaction between gametes during fertilization is at least in part regulated by carbohydrate moieties of the zona pellucida (ZP) and carbohydrate binding proteins of the sperm surface. This review focuses on the protein-carbohydrate interactions during
Kolle, S., Plendl, J., Sinowatz, Fred
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Sperm capacitation and the acrosome reaction [PDF]
Human Reproduction, 1998 To achieve successful fertilization under normal circumstances in vivo, mammalian spermatozoa must first undergo capacitation and then the acrosome reaction, an exocytotic event that allows cells to penetrate the zona pellucida and fuse with the oocyte plasma membrane.
openaire +2 more sources