Results 61 to 70 of about 218,627 (165)
Andrology, EarlyView.ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu +8 more
wiley +1 more source
Sperm Adhesion Molecule 1 (SPAM1) Distribution in Selected Human Sperm by Hyaluronic Acid Test
Biomedicines, 2022 The failures of binding to the oocyte zona pellucida are commonly attributed to defects in the sperm recognition, adhesion, and fusion molecules. SPAM1 (sperm adhesion molecule 1) is a hyaluronidase implicated in the dispersion of the cumulus-oocyte ...
María José Gómez-Torres +5 more
doaj +1 more source
Impact of Sorting and Catch Media on Porcine Sperm Motility, Capacitation, and Viability
Andrology, EarlyView.ABSTRACT Background Fluorescence‐activated cell sorting (FACS) has emerged as a powerful tool for selecting spermatozoa of a desired population of fluorescent biomarkers, offering potential applications in reproductive biology and agriculture. However, concerns remain regarding sorting‐induced physiological alterations that could compromise spermatozoa
Tyler Weide, Juan Steibel, Karl Kerns
wiley +1 more source
Modifications of the 26S proteasome during boar sperm capacitation
Cell and Tissue Research, 2018 Protein ubiquitination is a stable, reversible post-translational modification, targeting proteins for degradation/recycling by the 26S proteasome in a well-characterized enzymatic cascade.
M. Zigo +3 more
semanticscholar +1 more source
Andrology, EarlyView.ABSTRACT Background Infertility is a pressing global health concern, affecting one in six couples worldwide. The failure rate for assisted reproductive technologies (ART) cycles remains at approximately 78%, with limited improvements often attributed to a lack of technological innovation.
Mehran Dabiri +3 more
wiley +1 more source
PLoS ONE, 2021 In boar sperm, we have previously shown that capacitation is associated with the appearance of the p32 tyrosine phosphoprotein complex. The principal tyrosine phosphoprotein involved in this complex is the acrosin-binding protein (ACRBP), which regulates
Yoku Kato +3 more
doaj +1 more source
Lysine acetylation modulates mouse sperm capacitation
Scientific Reports, 2018 Mammalian sperm are unable to fertilize the egg immediately after ejaculation. To gain fertilization competence, they need to undergo a series of modifications inside the female reproductive tract, known as capacitation.
Carla Ritagliati +5 more
semanticscholar +1 more source
Andrology, EarlyView.ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda +7 more
wiley +1 more source
Scientific Reports, 2021 Upon insemination, sperm cells are exposed to components of the female reproductive tract (FRT) fluids, such as urea and epidermal growth factor (EGF).
Rasoul Kowsar +4 more
doaj +1 more source
Serine Protease Inhibitor SERPINE2 Reversibly Modulates Murine Sperm Capacitation
International Journal of Molecular Sciences, 2018 SERPINE2 (serpin peptidase inhibitor, clade E, member 2), predominantly expressed in the seminal vesicle, can inhibit murine sperm capacitation, suggesting its role as a sperm decapacitation factor (DF).
Sheng-Hsiang Li +5 more
semanticscholar +1 more source