Results 81 to 90 of about 134,084 (212)

GSK3α‐mediated regulation of the RNA demethylase fat mass and obesity‐associated protein (FTO) during murine spermatogenesis

The FEBS Journal, EarlyView.
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari, Budheswar Dehury, Rounak Roy, Radhakrishnan Periyasamy, Indrashis Bhattacharya, Mahesh Sahare, Srinivasan Vijayraghavan, Souvik Dey   +7 more
wiley   +1 more source

Reduced glutathione and cysteine hydrochloride on crossbred bull semen [PDF]

, 2012
Over the last few years, good quality freezable semen was not utilized effectively due to less knowledge about the freezability of semen. One reason is the lack of sufficient antioxidants in the seminal plasma and semen extender.
P Perumal
core   +1 more source

Reorganization of mouse sperm lipid rafts by capacitation [PDF]

, 2006
One of the hallmarks of mammalian sperm capacitation is the loss of cholesterol from the plasma membrane. Cholesterol has been associated with the formation of detergent insoluble membrane microdomains in many cell types, and sperm from several mammalian
Thomas, Monzy, Thaler, Catherine D., Ramalie, Jenniffer R.   +2 more
core   +2 more sources

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

The Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington, Harold A. Coleman, Penelope M. Sheehan, Shaun P. Brennecke, Marianne Tare   +4 more
wiley   +1 more source

Safe and Stable Germline Transmission of MSTN Mutations in Cattle

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT With the global population expected to reach 10 billion by 2050, sustainable livestock production is critical. Gene editing of the myostatin (MSTN) gene represents a promising strategy to enhance muscle growth in cattle. In this study, MSTN‐mutated founder (F0) cows were used to generate F1 offspring via ovum pick‐up, in vitro fertilization ...
Gyeong‐Min Gim, Bae Young Choi, Jeongbin Yi, Kyeong‐Hyeon Eom, Soo‐Young Yum, Dae‐Jin Jung, Do‐Yoon Kim, Bokyoung Yang, Jong‐Seo Kim, Donghwan Shim, Goo Jang   +10 more
wiley   +1 more source

Bioprospecting snakehead fish protein concentrate (SFC) as a non non-serumserum-based albumin source for promoting capacitation in bovine sperm

Journal of the Indonesian Tropical Animal Agriculture
Capacitation is a prerequisite for successful fertilization with albumin as an inevitable component among the oviductal fluid's constituents. Under in vitroenvironments, albumin's function is replaced by serum-based products, which carry the issue of ...
H. Setiawan, T. Lertwichaikul, M. Thongkham, P. Chuammitri, K. Sringarm, M. Intanon, A. Sathanawongs   +6 more
doaj   +1 more source

Sustainable Overproduction of the Bacterial Pigment Indigoidine as a Natural Colorant: Stability Evaluation, Inhibition of Obesity‐Diabetes‐Related Digestive Enzymes, and Activation of AMPK–AKT

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Production of indigoidine (IND) increased from 1.04 to 2.76 g/L using an optimized LB medium composed of glucose, l‐glutamine, tryptone, yeast extract, MgSO4·7H2O, and KH2PO4. The IND has significant inhibition properties against amylase and lipase enzymes, stimulates AMPK and AKT pathways, and improves glucose uptake.
Tahani Ali Asseri
wiley   +1 more source

Niemann–Pick type C2-mediated cholesterol sequestration induces capacitation-like sperm remodeling during reproductive tract transit in the blue swimming crab (Portunus pelagicus) [PDF]

Veterinary World
Background and Aim: Cholesterol (CHO) sequestration from the sperm plasma membrane is a fundamental event during mammalian sperm capacitation, but the molecular mechanisms underlying capacitation-like sperm activation in brachyuran crabs remain unknown ...
Wattana Weerachatyanukul, Thanyaporn Senarai, Thitiporn Khongkha, Orawan Thongsum, Supawich Boonkua, Jirawat Saetan, Piyaporn Surinlert, Somluk Asuvapongpatana   +7 more
doaj   +1 more source

Global Proteomic Analysis of Sperm and Seminal Plasma From Tropically‐Adapted Rams With Contrasting Parameters of Frozen‐Thawed Semen

Molecular Reproduction and Development, Volume 93, Issue 10, October 2026.
ABSTRACT The aim of this study was to characterize the proteome of sperm and seminal plasma (SP) from rams with high semen freezability (HF) and low semen freezability (LF). Eleven ejaculates were collected from 12 rams, at 3‐day intervals, and cryopreserved (132 semen samples).
Wallisson Bruno de Morais Pacheco, Iran Aguila Maciel, Suane Santos Alves dos Santos, Alan Martins de Araújo, Francisca Nágila Matos Almeida, Denise Damasceno Guerreiro, Sheheryar Sheheryar, Lais Lacerda Brasil de Oliveira, Felipe Domingos de Sousa, Mohibullah Shah, Maria Elisabete Amaral Moraes, Carlos Roberto Koscky Paier, Ana Cristina de Oliveira Monteiro, Carminda Sandra Brito Salmito‐Vanderley, Arlindo A. Moura   +14 more
wiley   +1 more source

CRISPR/Cas9‐mediated Genome‐editing Reveals 10 Testis‐enriched Genes and One Non‐testis‐enriched Gene are Dispensable for Male Fecundity in Mice

Andrology, Volume 14, Issue 7, Page 2150-2159, October 2026.
ABSTRACT Background More than 1000 genes have been identified as predominantly expressed in the human testis. Advances in gene editing technologies have enabled the rapid and efficient generation of genetically engineered mice. This approach facilitates the screening of genes essential for spermatogenesis by analyzing knockout mouse models.
Yumiao Qiu, Keisuke Shimada, Masahito Ikawa   +2 more
wiley   +1 more source