Results 91 to 100 of about 134,084 (212)

Seminal Plasma Exosomal miRNA Profiling Reveals hsa‐miR‐7‐5p as a Key Regulator of Sperm Motility in Asthenozoospermia

Andrology, Volume 14, Issue 7, Page 2166-2179, October 2026.
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu, Meng‐Li Cui, Wen‐Jing Yuan, Jia‐Ning Zhang, Shuo Zhang, Xi‐Qiao Yao, Ruo‐Qing Li, Jin‐Feng Li, En‐Zhong Li   +8 more
wiley   +1 more source

Impact of Sorting and Catch Media on Porcine Sperm Motility, Capacitation, and Viability

Andrology, Volume 14, Issue 7, Page 2207-2220, October 2026.
ABSTRACT Background Fluorescence‐activated cell sorting (FACS) has emerged as a powerful tool for selecting spermatozoa of a desired population of fluorescent biomarkers, offering potential applications in reproductive biology and agriculture. However, concerns remain regarding sorting‐induced physiological alterations that could compromise spermatozoa
Tyler Weide, Juan Steibel, Karl Kerns
wiley   +1 more source

Microfluidic Intracytoplasmic Sperm Injection (MICSI): A Novel Platform for Sperm Isolation, Selection, and Injection Into Oocytes

Andrology, Volume 14, Issue 7, Page 2252-2261, October 2026.
ABSTRACT Background Infertility is a pressing global health concern, affecting one in six couples worldwide. The failure rate for assisted reproductive technologies (ART) cycles remains at approximately 78%, with limited improvements often attributed to a lack of technological innovation.
Mehran Dabiri, Dale Mark Goss, Steven Alexander Vasilescu, Majid Ebrahimi Warkiani   +3 more
wiley   +1 more source

Regulation of Sperm Capacitation and the Acrosome Reaction by PIP 2 and Actin Modulation

Asian Journal of Andrology, 2015
Actin polymerization and development of hyperactivated (HA) motility are two processes that take place during sperm capacitation. Actin polymerization occurs during capacitation and prior to the acrosome reaction, fast F-actin breakdown takes place.
Haim Breitbart, Maya Finkelstein
doaj   +1 more source

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

Andrology, Volume 14, Issue 7, Page 2329-2346, October 2026.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan, Nini Wei, Weiwei Ma, Mengting Hu, Bei Zhang, Li Gao, Chao Gao, Xiaoyu Yang, Yan Meng, Jiayin Liu, Yugui Cui   +10 more
wiley   +1 more source

Seminal Extracellular Vesicles as Molecular Modulators of Male Reproductive Function

Reproduction in Domestic Animals, Volume 61, Issue S3, October 2026.
ABSTRACT Extracellular vesicles (sEVs) contained in seminal plasma (SP) maintain, in concert with free SP‐components (proteins, hormones, cytokines, metabolites and antioxidants) under an endocrine umbrella the functional in vivo homeostasis of ejaculated spermatozoa. The sEVs define a generic mixture of nanovesicles delivered by male epithelial cells,
Heriberto Rodriguez‐Martinez, Jordi Roca, Fernando Peña Vega, Emilio A. Martinez   +3 more
wiley   +1 more source

Effect of capacitation on the endocannabinoid system of mouse sperm

, 2011
The presence of the elements of the endocannabinoid system (ECS) in sperm isolated from several species (from invertebrates to mammals, humans included) has supported the ‘‘evolutionary theory’’ that proposes endocannabinoids as check points in ...
Rossi G, Catanzaro G, Di Tommaso M, Cecconi S, Maccarrone M., Pirazzi V, PUCCI, MARIANGELA, BATTISTA, Natalia   +7 more
core   +2 more sources

Small and Large Seminal Extracellular Vesicles Differentially Modulate Capacitation‐Related Parameters in Frozen–Thawed Porcine Epididymal Spermatozoa

Reproduction in Domestic Animals, Volume 61, Issue S3, October 2026.
ABSTRACT Seminal extracellular vesicles (sEVs) have been proposed as modulators of sperm function, but their exact role remains unclear. Most studies use ejaculated sperm for clarification. This approach has limitations; nevertheless, as ejaculated sperm have already been exposed to their own native sEVs, which hinders the assessment of their specific ...
Patricia Panales, Junwei Li, Ana Parra, Pablo Martínez‐Díaz, Xiomara Lucas, Marc Yeste, Jordi Roca, Isabel Barranco   +7 more
wiley   +1 more source

Serine Protease Inhibitor SERPINE2 Reversibly Modulates Murine Sperm Capacitation

, 2018
SERPINE2 (serpin peptidase inhibitor, clade E, member 2), predominantly expressed in the seminal vesicle, can inhibit murine sperm capacitation, suggesting its role as a sperm decapacitation factor (DF).
Chung-Hao Lu, Robert Kuo-Kuang Lee, Yuh-Ming Hwu, Ling-Yu Yeh, Sheng-Hsiang Li, Ming-Huei Lin, Robert Lee   +6 more
core   +1 more source

Restoration of Motility in Acrosome‐Reacted Boar Spermatozoa Induced by the Ionophore 4‐Br‐A23187

Reproduction in Domestic Animals, Volume 61, Issue S3, October 2026.
ABSTRACT The acrosome reaction (AR) is a calcium‐dependent exocytotic event required for successful fertilization. Calcium ionophores are commonly used to induce AR in vitro; however, this treatment is associated with a significant loss of sperm motility. The aim of this study was to evaluate the recovery of motility in boar spermatozoa after ionophore‐
David Martín‐Hidalgo, Violeta Calle‐Guisado, Beatriz Macías‐García, Lauro González‐Fernández   +3 more
wiley   +1 more source