The FASEB Journal, Volume 40, Issue 8, 30 April 2026.Graphical abstract illustrating the barrier defense–tolerance framework of reproductive innate immunity. Across the female and male reproductive tracts and the maternal–fetal interface, epithelial barriers, innate sensors, immune cells, and microbial signals are integrated to preserve reproductive homeostasis.
Xianlin Rao +3 more
wiley +1 more source
The effect of leukaemia inhibitory factor (LIF) on bovine embryo development in vitro : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Animal Science at Massey University [PDF]
, 1995 The aim of the study was to investigate the effect of Leukaemia Inhibitory Factor (LIF) either during in vitro maturation (IVM) or in vitro culture (IVC) on bovine embryo development. Three main experiments were conducted using oocytes aspirated from 2-8
Margawati, Endang Tri
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Analysis of the mechanism by which calcium negatively regulates the tyrosine phosphorylation cascade associated with sperm capacitation [PDF]
, 2004 The capacitation of mammalian spermatozoa involves the activation of a cAMP-mediated signal transduction pathway that drives tyrosine phosphorylation via mechanisms that are unique to this cell type.
Aitken, R. John +4 more
core +2 more sources
A cost for high levels of sperm competition in rodents: Increased sperm DNA fragmentation [PDF]
, 2016 Spermcompetition, a prevalent evolutionary process inwhich the spermatozoa of two or more males compete for the fertilization of the same ovum, leads to morphological and physiological adaptations, including increases in energetic metabolism that may ...
Delbarco-Trillo, Javier +5 more
core +1 more source
Ca2+ ionophore A23187 can make mouse spermatozoa capable of fertilizing in vitro without activation of cAMP-dependent phosphorylation pathways [PDF]
, 2013 Ca2+ ionophore A23187 is known to induce the acrosome reaction of mammalian spermatozoa, but it also quickly immobilizes them. Although mouse spermatozoa were immobilized by this ionophore, they initiated vigorous motility (hyperactivation) soon after ...
Darszon, Alberto +6 more
core +2 more sources
Partial Deletion of Chromosome 8 β-defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice [PDF]
, 2013 β-defensin peptides are a family of antimicrobial peptides present at mucosal surfaces, with the main site of expression under normal conditions in the male reproductive tract.
A Krutskikh +59 more
core +5 more sources
Compartmentalization of distinct cAMP signaling pathways in mammalian sperm. [PDF]
, 2013 Fertilization competence is acquired in the female tract in a process known as capacitation. Capacitation is needed for the activation of motility (e.g. hyperactivation) and to prepare the sperm for an exocytotic process known as acrosome reaction. While
Buck, Jochen +12 more
core +1 more source
Frontiers in Veterinary ScienceCapacitation is the process by which sperm undergoes physical, biochemical, and molecular changes to acquire the ability to fertilize an oocyte.
Abdulkadir Kaya +5 more
doaj +1 more source
Potassium ion influx and Na+,K+-ATPase activity are required for the hamster sperm acrosome reaction. [PDF]
, 1981 The role of a K+ ion influx and Na+,K+-ATPase activity in the hamster sperm acrosome reaction (AR) was examined, using a range of concentrations of K+,K+ ionophores and a Na+,K+-ATPase inhibitor.
Meizel, S, Mrsny, RJ
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A Fluorometric Method for Measurement of Sperm Capacitation
Experimental Biology and Medicine, 1967 SummaryA fluorometric technique for measurement of sperm capacitation is described. Rabbit sperm were labeled with tetracycline HCI (T-HCI) and placed in uteri and oviducts of estrous and pseudopregnant does and in other regions of estrous females.
openaire +2 more sources