Mechanisms That Protect Mammalian Sperm from the Spontaneous Acrosome Reaction. [PDF]
Int J Mol Sci, 2023 To acquire the capacity to fertilize the oocyte, mammalian spermatozoa must undergo a series of biochemical reactions in the female reproductive tract, which are collectively called capacitation. The capacitated spermatozoa subsequently interact with the
Breitbart H, Grinshtein E.
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Human Zona Pellucida Glycoproteins: Binding Characteristics With Human Spermatozoa and Induction of Acrosome Reaction [PDF]
Frontiers in Cell and Developmental Biology, 2021 Human zona pellucida (ZP) matrix is composed of four glycoproteins designated as ZP glycoprotein -1 (ZP1), -2 (ZP2), -3 (ZP3), and -4 (ZP4). Mutations in the genes encoding human ZP glycoproteins are one of the causative factors leading to abnormal ZP ...
Satish Kumar Gupta
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Glycogen Synthase Kinase-3 Regulates Sperm Motility and Acrosome Reaction via Affecting Energy Metabolism in Goats [PDF]
Frontiers in Physiology, 2019 Hyperactivation and acrosome reaction of sperm are pre-requisite steps for fertilization. However, the hyperactivation and acrosome reaction are critically controlled through the phosphorylation of specific proteins.
Zhendong Zhu +7 more
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Testis-enriched ferlin, FER1L5, is required for Ca<sup>2+</sup>-activated acrosome reaction and male fertility. [PDF]
Sci Adv, 2023 Spermatozoa need to undergo an exocytotic event called the acrosome reaction before fusing with eggs. Although calcium ion (Ca2+) is essential for the acrosome reaction, its molecular mechanism remains unknown.
Morohoshi A +6 more
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Lipidomics profiles of human spermatozoa: insights into capacitation and acrosome reaction using UPLC-MS-based approach [PDF]
Frontiers in Endocrinology, 2023 IntroductionLipidomics elucidates the roles of lipids in both physiological and pathological processes, intersecting with many diseases and cellular functions.
Xiaohong Cheng +8 more
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Heat shock affects the Ca2+/calmodulin-dependent protein kinase II dynamic during bovine sperm capacitation and acrosome reaction [PDF]
Frontiers in Cell and Developmental BiologyBackgroundHeat shock during sperm capacitation affects the spermatozoa quality, resulting in increased early acrosome reaction and consequently decreasing their fertilizing capacity.
Thais de Sousa Santos +5 more
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Influence of different cellular concentrations of boar sperm suspensions on the induction of capacitation and acrosome reaction [PDF]
The Journal of Reproduction and Development, 2021 We aimed to analyze the influence of different cellular concentrations of boar sperm suspensions on the induction of capacitation and acrosome reaction.
David MARTÍN-HIDALGO +2 more
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Role of cytoskeleton-related proteins in the acrosome reaction of Eriocheir sinensis spermatozoa [PDF]
BMC Genomic Data, 2023 Cytoskeleton-related proteins are essential for cell shape maintenance and cytoskeleton remodeling. The spermatozoa of Eriocheir sinensis (Chinese mitten crab) have a unique cellular structure, and the mechanism of spermatozoal metamorphosis during the ...
Yulian Tang +6 more
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Modulation of spermatozoon acrosome reaction [PDF]
Biological Research, 2011 Spermatozoon acrosome reaction is an exocytotic event of the utmost importance for the development of mammalian fertilisation. Current evidence shows that the triggering of the acrosome reaction (AR) could be regulated by the action of diverse compounds,
Pilar Vigil +2 more
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Influence of Cryopreservation on the Acrosome Reaction in Hucul Stallion Spermatozoa [PDF]
AnimalsThe Hucul horse is a Polish primitive breed with a small population size, which highlights the importance of preserving the genetic resources. The cryopreservation of semen is essential for creating gene banks, but its effect on the acrosome reaction in ...
Monika Bugno-Poniewierska +5 more
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