Results 41 to 50 of about 5,280,557 (249)

Characterization of CD46 and β1 integrin dynamics during sperm acrosome reaction

open access: yesScientific Reports, 2016
The acrosome reaction (AR) is a process of membrane fusion and lytic enzyme release, which enables sperm to penetrate the egg surroundings. It is widely recognized that specific sperm proteins form an active network prior to fertilization and their ...
M. Frolikova   +3 more
semanticscholar   +1 more source

Repression of autophagy leads to acrosome biogenesis disruption caused by a sub-chronic oral administration of polystyrene nanoparticles.

open access: yesEnvironment International, 2022
As a new widespread contaminant, nanoplastics (NPs) pose a potential risk to human health. Nevertheless, the adverse effects of NPs on the male reproductive system are poorly understood.
Lixiao Zhou   +12 more
semanticscholar   +1 more source

Human sperm ion channel (dys)function:implications for fertilization [PDF]

open access: yes, 2019
BACKGROUND: Intensive research on sperm ion channels has identified members of several ion channel families in both mouse and human sperm. Gene knock-out studies have unequivocally demonstrated the importance of the calcium and potassium conductances in ...
Barratt, Christopher L. R.   +3 more
core   +4 more sources

EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner

open access: yesEndocrine Connections, 2017
Human sperm cell function must be precisely regulated to achieve natural fertilization. Progesterone released by the cumulus cells surrounding the egg induces a Ca2+ influx into human sperm cells via the CatSper Ca2+-channel and thereby controls sperm ...
A Rehfeld   +5 more
doaj   +1 more source

Exceptional sperm cooperation in the wood mouse [PDF]

open access: yes, 2002
Spermatozoa from a single male will compete for fertilization of ova with spermatozoa from another male when present in the female reproductive tract at the same time.
AH Harcourt   +32 more
core   +1 more source

The biochemistry of the acrosome reaction [PDF]

open access: yesMolecular Human Reproduction, 1997
The binding of the spermatozoon to the oocyte zona pellucida (ZP) occurs via specific receptors localized over the anterior head region of the spermatozoon. Zona pellucida binding stimulates the spermatozoa to undergo the acrosome reaction resulting in the release of hydrolytic enzymes and in the exposure of new membrane domains, both of which are ...
H, Breitbart, B, Spungin
openaire   +2 more sources

Protein-carbohydrate interactions during fertilization [PDF]

open access: yes, 1998
Interaction between gametes during fertilization is at least in part regulated by carbohydrate moieties of the zona pellucida (ZP) and carbohydrate binding proteins of the sperm surface. This review focuses on the protein-carbohydrate interactions during
Kolle, S., Plendl, J., Sinowatz, Fred
core   +1 more source

Chronic restraint stress induces sperm acrosome reaction and changes in testicular tyrosine phosphorylated proteins in rats

open access: yesInternational Journal of Reproductive BioMedicine, 2016
Background: Stress is a cause of male infertility. Although sex hormones and sperm quality have been shown to be low in stress, sperm physiology and testicular functional proteins, such as phosphotyrosine proteins, have not been documented. Objective: To
S. Arun   +5 more
semanticscholar   +1 more source

Cryoprotectant-free vitrification of human spermatozoa in new artificial seminal fluid [PDF]

open access: yes, 2016
Vitrification is a new method that has been recently introduced in Assisted Reproduction Technique programs. The aim of this study was to design a new medium similar to normal human seminal fluid (SF), formulation artificial seminal fluid (ASF), and to ...
Agha Rahimi, A.   +4 more
core   +1 more source

Evidence of the presence of calcium/calmodulin-dependent protein kinase IV in human sperm and its involvement in motility regulation [PDF]

open access: yes, 2005
The mechanisms involved in the regulation of mammalian sperm motility are not well understood. Calcium ions (Ca(2+)) have been suggested to play a key role in the maintenance of motility; nevertheless, how Ca(2+) modulates this process has not yet been ...
Buffone, Mariano Gabriel   +6 more
core   +1 more source

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