Results 21 to 30 of about 512 (91)

Lipidomics profiles of human spermatozoa: insights into capacitation and acrosome reaction using UPLC-MS-based approach

open access: yesFrontiers in Endocrinology, 2023
IntroductionLipidomics elucidates the roles of lipids in both physiological and pathological processes, intersecting with many diseases and cellular functions.
Xiaohong Cheng   +8 more
doaj   +1 more source

Influence of different cellular concentrations of boar sperm suspensions on the induction of capacitation and acrosome reaction

open access: yesThe Journal of Reproduction and Development, 2021
We aimed to analyze the influence of different cellular concentrations of boar sperm suspensions on the induction of capacitation and acrosome reaction.
David MARTÍN-HIDALGO   +2 more
doaj   +1 more source

Bovine Follicular Fluid Derived Extracellular Vesicles Modulate the Viability, Capacitation and Acrosome Reaction of Bull Spermatozoa

open access: yesBiology, 2021
While follicular fluid (FF) is known to enhance the functional properties of spermatozoa, the role of FF-derived extracellular vesicles (EVs) in this respect is unknown.
Mohammad Mehedi Hasan   +8 more
doaj   +1 more source

Expression of TRPV1 as A Heat Sensitive Voltage-Dependent Ion Channel and Oxidative Stress in Sperm Samples of Infertile Men with Varicocele: A Case-Control Study [PDF]

open access: yesCell Journal, 2022
Objective: Transient receptor potential vanilloid 1 (TRPV1) is a heat-activated nonselective cation channel that playsimportant role in the spermatogenesis, capacitation, acrosome reaction and sperm/oocyte fusion.
Sahar Salahshouri   +4 more
doaj   +1 more source

Glycogen Synthase Kinase-3 Regulates Sperm Motility and Acrosome Reaction via Affecting Energy Metabolism in Goats

open access: yesFrontiers in Physiology, 2019
Hyperactivation and acrosome reaction of sperm are pre-requisite steps for fertilization. However, the hyperactivation and acrosome reaction are critically controlled through the phosphorylation of specific proteins.
Zhendong Zhu   +7 more
doaj   +1 more source

Effect of phosphodiesterase type 5 inhibitors on sperm motility and acrosome reaction: An in vitro study [PDF]

open access: yesInvestigative and Clinical Urology, 2021
Purpose: Phosphodiesterase type 5 (PDE5) inhibitors are effective treatments for erectile dysfunction, and several recent studies have reported positive effects of PDE5 inhibitors on semen parameters as well. However, the data are still controversial. We
Seung-Hun Song   +8 more
doaj   +1 more source

EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner

open access: yesEndocrine Connections, 2017
Human sperm cell function must be precisely regulated to achieve natural fertilization. Progesterone released by the cumulus cells surrounding the egg induces a Ca2+ influx into human sperm cells via the CatSper Ca2+-channel and thereby controls sperm ...
A Rehfeld   +5 more
doaj   +1 more source

JAGGED1 modulates bull spermatozoa acrosome reaction and fertilization

open access: yesReproduction and Fertility
To acquire fertilizing ability, mammalian spermatozoa (SPZ) must undergo acrosome reaction, which is associated with protein remodeling and relocation. Previous studies showed that Notch ligand JAGGED1 is relocated from the apical to the post-equatorial ...
Patrícia Diniz   +5 more
doaj   +1 more source

Role of cytoskeleton-related proteins in the acrosome reaction of Eriocheir sinensis spermatozoa

open access: yesBMC Genomic Data, 2023
Cytoskeleton-related proteins are essential for cell shape maintenance and cytoskeleton remodeling. The spermatozoa of Eriocheir sinensis (Chinese mitten crab) have a unique cellular structure, and the mechanism of spermatozoal metamorphosis during the ...
Yulian Tang   +6 more
doaj   +1 more source

CD147 deficiency is associated with impairedsperm motility/acrosome reaction and offersa therapeutic target for asthenozoospermia

open access: yesMolecular Therapy: Nucleic Acids, 2021
Patients with asthenozoospermia often present multiple defects in sperm functions apart from a decrease in sperm motility. However, the etiological factors underlying these multifaceted defects remain mostly unexplored, which may lead to unnecessary ...
Hao Chen   +16 more
doaj   +1 more source

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