Bovine Follicular Fluid Derived Extracellular Vesicles Modulate the Viability, Capacitation and Acrosome Reaction of Bull Spermatozoa [PDF]
Biology, 2021 While follicular fluid (FF) is known to enhance the functional properties of spermatozoa, the role of FF-derived extracellular vesicles (EVs) in this respect is unknown.
Mohammad Mehedi Hasan +8 more
doaj +4 more sources
Participation of the inositol 1,4,5-trisphosphate-gated calcium channel in the zona pellucida- and progesterone-induced acrosome reaction and calcium influx in human spermatozoa [PDF]
Asian Journal of Andrology, 2020 The acrosome reaction is a prerequisite for fertilization, and its signaling pathway has been investigated for decades. Regardless of the type of inducers present, the acrosome reaction is ultimately mediated by the elevation of cytosolic calcium ...
Ying-Ya Li +3 more
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CD147 deficiency is associated with impairedsperm motility/acrosome reaction and offersa therapeutic target for asthenozoospermia [PDF]
Molecular Therapy: Nucleic Acids, 2021 Patients with asthenozoospermia often present multiple defects in sperm functions apart from a decrease in sperm motility. However, the etiological factors underlying these multifaceted defects remain mostly unexplored, which may lead to unnecessary ...
Hao Chen +16 more
doaj +2 more sources
Effect of phosphodiesterase type 5 inhibitors on sperm motility and acrosome reaction: An in vitro study [PDF]
Investigative and Clinical Urology, 2021 Purpose: Phosphodiesterase type 5 (PDE5) inhibitors are effective treatments for erectile dysfunction, and several recent studies have reported positive effects of PDE5 inhibitors on semen parameters as well. However, the data are still controversial. We
Seung-Hun Song +8 more
doaj +3 more sources
MicroRNAs and Their Associated Genes Regulating the Acrosome Reaction in Sperm of High- versus Low-Fertility Holstein Bulls [PDF]
AnimalsBioinformatics envisage experimental data as illustrated biological networks, exploring roles of individual proteins and their interactions with other proteins in regulation of biological functions.
Vanmathy Kasimanickam +1 more
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Partial deletion of chromosome 8 β-defensin cluster confers sperm dysfunction and infertility in male mice. [PDF]
PLoS Genetics, 2013 β-defensin peptides are a family of antimicrobial peptides present at mucosal surfaces, with the main site of expression under normal conditions in the male reproductive tract.
Yu S Zhou +16 more
doaj +7 more sources
Artemisia vulgaris extract causes precocious acrosome reaction and viability loss but low rate of membrane damage in mouse spermatozoa [PDF]
Journal of Animal Science and Technology, 2021 Several herbs including Artemisia are known to possess conceptive property. In the present study, mouse spermatozoa were incubated with ethanol extract of Artemisia vulgaris leaves. The effect of
Sabina Bhandari +4 more
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Effect of Lepidium meyenii on in vitro fertilization via improvement in acrosome reaction and motility of mouse and human sperm [PDF]
Reproductive Medicine and Biology, 2019 Purpose The direct effects of Lepidium meyenii (Maca) on sperm remain unclear. Herein, we examined the direct effect of Maca on in vitro fertilization. Methods We examined the fertilization rate in a mouse model and the rate of acrosome reaction in sperm
Yusuke Aoki +10 more
doaj +2 more sources
Nitric oxide involvement in the acrosome reaction triggered by leptin in pig sperm
Reproductive Biology and Endocrinology, 2011 Background Nitric oxide (NO) is a signaling molecule produced by intracellular nitric oxide synthase (NOS) enzymes. This free radical appears to affect sperm capacitation, a maturation step preceding acrosome reaction. Recent studies have reported leptin
Guido Carmela +4 more
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Mouse sperm membrane potential hyperpolarization is necessary and sufficient to prepare sperm for the acrosome reaction [PDF]
Journal of Biological Chemistry, 2012 Mammalian sperm are unable to fertilize the egg immediately after ejaculation; they acquire this capacity during migration in the female reproductive tract. This maturational process is called capacitation and in mouse sperm it involves a plasma membrane
Darszon, Alberto +7 more
core +2 more sources