CD147 deficiency is associated with impairedsperm motility/acrosome reaction and offersa therapeutic target for asthenozoospermia [PDF]
Molecular Therapy: Nucleic Acids, 2021 Patients with asthenozoospermia often present multiple defects in sperm functions apart from a decrease in sperm motility. However, the etiological factors underlying these multifaceted defects remain mostly unexplored, which may lead to unnecessary ...
Hao Chen +16 more
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Effect of phosphodiesterase type 5 inhibitors on sperm motility and acrosome reaction: An in vitro study [PDF]
Investigative and Clinical Urology, 2021 Purpose: Phosphodiesterase type 5 (PDE5) inhibitors are effective treatments for erectile dysfunction, and several recent studies have reported positive effects of PDE5 inhibitors on semen parameters as well. However, the data are still controversial. We
Seung-Hun Song +8 more
doaj +2 more sources
Glycogen Synthase Kinase-3 Regulates Sperm Motility and Acrosome Reaction via Affecting Energy Metabolism in Goats [PDF]
Frontiers in Physiology, 2019 Hyperactivation and acrosome reaction of sperm are pre-requisite steps for fertilization. However, the hyperactivation and acrosome reaction are critically controlled through the phosphorylation of specific proteins.
Zhendong Zhu +7 more
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MicroRNAs and Their Associated Genes Regulating the Acrosome Reaction in Sperm of High- versus Low-Fertility Holstein Bulls [PDF]
AnimalsBioinformatics envisage experimental data as illustrated biological networks, exploring roles of individual proteins and their interactions with other proteins in regulation of biological functions.
Vanmathy Kasimanickam +1 more
doaj +2 more sources
Artemisia vulgaris extract causes precocious acrosome reaction and viability loss but low rate of membrane damage in mouse spermatozoa [PDF]
Journal of Animal Science and Technology, 2021 Several herbs including Artemisia are known to possess conceptive property. In the present study, mouse spermatozoa were incubated with ethanol extract of Artemisia vulgaris leaves. The effect of
Sabina Bhandari +4 more
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Effect of Lepidium meyenii on in vitro fertilization via improvement in acrosome reaction and motility of mouse and human sperm [PDF]
Reproductive Medicine and Biology, 2019 Purpose The direct effects of Lepidium meyenii (Maca) on sperm remain unclear. Herein, we examined the direct effect of Maca on in vitro fertilization. Methods We examined the fertilization rate in a mouse model and the rate of acrosome reaction in sperm
Yusuke Aoki +10 more
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Mechanisms That Protect Mammalian Sperm from the Spontaneous Acrosome Reaction [PDF]
International Journal of Molecular Sciences, 2023 Haim Breitbart
exaly +2 more sources
Journal of Animal Reproduction and Biotechnology, 2022 This study investigated the influence of sodium bicarbonate (NaHCO3) and progesterone on acrosome reaction and proportion of polyunsaturated fatty acid (PUFA) composition boar sperm.
Choon-Keun Park, Sang-Hee Lee
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The biochemistry of the acrosome reaction [PDF]
Molecular Human Reproduction, 1997 The binding of the spermatozoon to the oocyte zona pellucida (ZP) occurs via specific receptors localized over the anterior head region of the spermatozoon. Zona pellucida binding stimulates the spermatozoa to undergo the acrosome reaction resulting in the release of hydrolytic enzymes and in the exposure of new membrane domains, both of which are ...
H, Breitbart, B, Spungin
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The Modulation of Functional Status of Bovine Spermatozoa by Progesterone
Animals, 2021 The aim of this study is to identify the effects of progesterone (PRG) on the capacitation and the acrosome reaction in bovine spermatozoa. The fresh sperm samples were incubated with and without capacitation inductors (heparin, dibutyryl cyclic ...
Vitaly Denisenko +5 more
doaj +1 more source