Results 71 to 80 of about 11,716,491 (307)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Effects of internal concentration polarization and membrane roughness on phenol removal in extractive membrane bioreactor

open access: yes, 2018
Recent studies have proved the advantages of novel composite membranes in the extractive membrane bioreactor (EMBR) for recalcitrant organic wastewater treatment.
Fane, Anthony Gordon   +9 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Metallic spacers to enhance membrane distillation

open access: yes, 2018
Despite membrane distillation (MD) being well acknowledged as a green technology due to the capability to treat water using waste heat, the efficient use of this heat remains one of the biggest challenge for MD to be cost-effective.
Tan, Yong Zen   +2 more
core   +1 more source

Optogenetic monitoring of membrane potentials [PDF]

open access: yesExperimental Physiology, 2010
Over the last decade, researchers in our laboratory have engineered and developed several series of genetically encoded voltage‐sensitive fluorescent proteins (VSFPs) by molecular fusion of a voltage‐sensing domain operand with different fluorescent reporter proteins.
Hiroki, Mutoh   +4 more
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

The organizing potential of sphingolipids in intracellular membrane transport [PDF]

open access: yes, 2010
Eukaryotes are characterized by endomembranes that are connected by vesicular transport along secretory and endocytic pathways. The compositional differences between the various cellular membranes are maintained by sorting events, and it has long been ...
Raggers, R.J.   +7 more
core  

Relating transport modeling to nanofiltration membrane fabrication : navigating the permeability-selectivity trade-off in desalination pretreatment

open access: yes, 2018
Faced with a pressing need for membranes with a higher permeability and selectivity, the field of membrane technology can benefit from a systematic framework for designing membranes with the necessary physical characteristics. In this work, we present an
Chang Liu   +7 more
core   +1 more source

Plasma membrane compartmentation in Saccharomyces cerevisiae [PDF]

open access: yes, 2009
In the plasma membrane of cells the complex variety of components is sorted into subcompartments, microdomains and nanoclusters. We only begin to understand the principles of this higher order.
Großmann, Guido
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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