Results 91 to 100 of about 11,716,491 (307)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Plantaricin NC8 from Lactobacillus plantarum causes cell membrane disruption to Micrococcus luteus without targeting lipid II [PDF]

, 2018
Plantaricin NC8, a two-peptide non-lantibiotic class IIb bacteriocin composed of PLNC8α and PLNC8β and derived from Lactobacillus plantarum ZJ316, has been shown to be highly potent against a range of bacteria and fungi.
Breukink, Eefjan, Sub Membrane Biochemistry & Biophysics, Li, Ping, Membrane Biochemistry and Biophysics, Tang, Xuan, Gu, Qing, Zhou, Qingqing, Jiang, Han, Zou, Jiong   +8 more
core   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Development of highly-efficient ZIF-8@PDMS/PVDF nanofibrous composite membrane for phenol removal in aqueous-aqueous membrane extractive process

, 2018
A highly-efficient zeolitic imidazolate framework-8 (ZIF-8) embedded polydimethylsiloxane (PDMS) mixed matrix membrane (MMM) supported by a polyvinylidene fluoride (PVDF) nanofibrous substrate was developed for phenol removal in an aqueous-aqueous ...
Tan, Choon-Hong, Wang, Rong, Jin, Meng-Yi, Lin, Yuqing, Liao, Yuan   +4 more
core   +1 more source

Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division [PDF]

, 2018
During the transition from elongation to septation, Escherichia coli establishes a ring-like peptidoglycan growth zone at the future division site.
Peters, Katharina, Casanova, Mercedes, Breukink, Eefjan, VanNieuwenhze, Michael, Vollmer, Waldemar, Sub Membrane Biochemistry & Biophysics, Membrane Biochemistry and Biophysics, Palacios, Pilar, Pazos, Manuel, Vicente, Miguel   +9 more
core   +1 more source

Heterogeneous Expression of T-type Ca2+ Channels Defines Different Neuronal Populations in the Inferior Olive of the Mouse

Frontiers in Cellular Neuroscience, 2016
The neurons in the inferior olive express subthreshold oscillations in their membrane potential. This oscillatory activity is known to drive synchronous activity in the cerebellar cortex and plays a role in motor learning and motor timing.
Paolo Bazzigaluppi, Marcel T G De Jeu
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Integral hollow fiber membrane with chemical cross-linking for pressure retarded osmosis operated in the orientation of active layer facing feed solution

, 2017
Pressure retarded osmosis (PRO) is an innovative technique to yield osmotic energy. Nevertheless, the PRO performance is exacerbated by the severe membrane fouling occurring within the porous support.
Setiawan, Laurentia, Li, Ye, Zhang, Lizhi, Lizhi Zhang, Ye Li, Rong Wang, Wang, Rong, Zhao, Shanshan, Shanshan Zhao, Laurentia Setiawan   +9 more
core   +1 more source

Corrigendum: A Novel Calcium-Activated Potassium Channel Controls Membrane Potential and Intracellular pH in Trypanosoma cruzi

Frontiers in Cellular and Infection Microbiology, 2021
Patricia Barrera, Christopher Skorka, Michael Boktor, Noopur Dave, Veronica Jimenez   +4 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source