Results 81 to 90 of about 2,440,422 (308)
With the increasing demand for freshwater, desalination of seawater and its alternatives has become a major priority for the scientific community. This work studied the preparation of a flat-sheet poly(vinylidene fluoride) (PVDF)/poly(methyl methacrylate)
Cheng, Tung-wen
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Cell membranes separate the inside and outside of cells. Membrane proteins in the cell membrane control the traffic of molecules across the membrane and are therefore targets for a lot of drugs: about 50 % of all approved drugs target a membrane protein!
Scheidelaar, S. +2 more
core
On the origin of membrane potential in membranes with polarizable nanopores [PDF]
We report a new mechanism for the generation of membrane potential in polarizable nanoporous membranes separating electrolytes with different concentrations.
Lebedev, D. V. +9 more
core +1 more source
Membrane distillation (MD) is a promising desalination technology as it is less sensitive to feed's salinity and can handle high-salinity water. However, the industrial application of MD is restricted by the limited availability of cost-effective ...
Zhao, Yali +5 more
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Six principles of visual cortical dynamics
A fundamental goal in vision science is to determine how many neurons in how many areas are required to compute a coherent interpretation of the visual scene.
Per E Roland
doaj +1 more source
Right-side-out plasma membrane Vesicles isolated from Zea mays roots were used to study membrane potential (Delta Psi)-dependent Ca2+ transport. Membrane potentials were imposed on the vesicles using either K+ concentration gradients and valinomycin or ...
Jacqueline Marshall +7 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source

