Results 51 to 60 of about 3,357,590 (333)

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Cell-Based Phenotyping Reveals QTL for Membrane Potential Maintenance Associated with Hypoxia and Salinity Stress Tolerance in Barley

Frontiers in Plant Science, 2017
Waterlogging and salinity are two major abiotic stresses that hamper crop production world-wide resulting in multibillion losses. Plant abiotic stress tolerance is conferred by many interrelated mechanisms.
Muhammad B. Gill, Muhammad B. Gill, Fanrong Zeng, Lana Shabala, Guoping Zhang, Yun Fan, Sergey Shabala, Meixue Zhou   +7 more
doaj   +1 more source

Study to elucidate effect of titanium dioxide nanoparticles on bacterial membrane potential and membrane permeability

Materials Research Express, 2020
The interaction of metal oxide nanoparticles (NPs) with cells and lipid bilayers is precarious in various fields such as antibacterial and drug or gene delivery.
Maya S Khater, Gauri R Kulkarni, Sagar S Khater, Haribhau Gholap, Rajendra Patil   +4 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Tension moderation and fluctuation spectrum in simulated lipid membranes under an applied electric potential

, 2013
We investigate the effect of an applied electric potential on the mechanics of a coarse grained POPC bilayer under tension. The size and duration of our simulations allow for a detailed and accurate study of the fluctuations.
Khandelia, Himanshu, Lomholt, Michael Andersen, Loubet, Bastien   +2 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Calcium‐ and voltage‐driven atrial alternans: Insight from [Ca]i and Vm asynchrony

Physiological Reports, 2023
Cardiac alternans is defined as beat‐to‐beat alternations in contraction strength, action potential duration (APD), and Ca transient (CaT) amplitude. Cardiac excitation–contraction coupling relies on the activity of two bidirectionally coupled excitable ...
G. Kanaporis, E. Martinez‐Hernandez, L. A. Blatter   +2 more
doaj   +1 more source

Dynamic Theory of Membrane Potentials

The Journal of Physical Chemistry B, 2010
An accurate understanding of the dynamics of membrane potential formation underpins modern electrophysiology and much of cell biochemistry. Computer simulations using a Nernst-Planck-Poisson (NPP) finite difference method are used to model the dynamic evolution of a series of membrane systems in which two reservoirs of electrolyte solution are ...
Ward, K, Dickinson, E, Compton, R
openaire   +3 more sources

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Ling’s Adsorption Theory as a Mechanism of Membrane Potential Generation Observed in Both Living and Nonliving Systems

Membranes, 2016
The potential between two electrolytic solutions separated by a membrane impermeable to ions was measured and the generation mechanism of potential measured was investigated.
Hirohisa Tamagawa, Makoto Funatani, Kota Ikeda   +2 more
doaj   +1 more source