Results 91 to 100 of about 438,564 (323)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Membrane Potential

open access: yes, 2014
Citation: 'membrane potential' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.M03825 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
A.A. Ramahi, R.L. Ruff
openaire   +2 more sources

Relationship Between Some Parameters of the Membrane-Redox Potentials Three-State Line System with the Human Constitutional Types of Traditional Medicine

open access: yesCentral Asian Journal of Medical Sciences, 2015
Objectives: According to Tibetan-Mongolian traditional medicine theory, humans are classified into three main individuals based on the Rlung, Mkhris or Badgan symbolic code (SC).
Narantsetseg Badarch   +3 more
doaj   +1 more source

Knocking down TRPM2 expression reduces cell injury and NLRP3 inflammasome activation in PC12 cells subjected to oxygen-glucose deprivation

open access: yesNeural Regeneration Research, 2020
Transient receptor potential melastatin 2 (TRPM2) is an important ion channel that represents a potential target for treating injury caused by cerebral ischemia.
Tao Pan   +7 more
doaj   +1 more source

Efficient potential of mean force calculation from multiscale simulations: solute insertion in a lipid membrane

open access: yes, 2017
The determination of potentials of mean force for solute insertion in a membrane by means of all-atom molecular dynamics simulations is often hampered by sampling issues.
Bereau, Tristan   +2 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Slow synaptic transmission in frog sympathetic ganglia [PDF]

open access: yes, 1986
Bullfrog ganglia contain two classes of neurone, B and C cells, which receive different inputs and exhibit different slow synaptic potentials. B cells, to which most effort has been directed, possess slow and late slow EPSPs.
Adams, P. R.   +5 more
core   +2 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Shengmaisan Regulates Pacemaker Potentials in Interstitial Cells of Cajal in Mice

open access: yesJournal of Pharmacopuncture, 2013
Objectives: Shengmaisan (SMS) is a traditional Chinese medicine prescription widely used for the treatment of diverse organs in Korea. The interstitial cells of Cajal (ICCs) are pacemaker cells that play an important role in the generation of coordinated
Kim Byung Joo
doaj   +1 more source

Determining K+ channel activation curves from K+ channel currents often requires the Goldman-Hodgkin-Katz equation

open access: yesFrontiers in Cellular Neuroscience, 2009
Potassium ion current in nerve membrane, IK, has traditionally been described by IK = gK(V-EK), where gK is the K ion conductance, V is membrane potential, and EK is the K+ Nernst potential. This description has been unchallenged by most investigators in
john r Clay
doaj   +1 more source

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