Results 101 to 110 of about 12,231,174 (337)

Reversibly Migratable Fluorescent Probe for Precise and Dynamic Evaluation of Cell Mitochondrial Membrane Potentials. [PDF]

Biosensors (Basel), 2022
Song G, He H, Chen W, Lv Y, Chu PK, Wang H, Li P.   +6 more
europepmc   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Multitask learning of a biophysically-detailed neuron model.

PLoS Computational Biology
The human brain operates at multiple levels, from molecules to circuits, and understanding these complex processes requires integrated research efforts.
Jonas Verhellen, Kosio Beshkov, Sebastian Amundsen, Torbjørn V Ness, Gaute T Einevoll   +4 more
doaj   +1 more source

Monitoring of compound resting membrane potentials of cell cultures with ratiometric genetically encoded voltage indicators. [PDF]

Commun Biol, 2021
Rühl P, Langner JM, Reidel J, Schönherr R, Hoshi T, Heinemann SH.   +5 more
europepmc   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Mechanism of antibacterial action of the alcoholic extracts of Hemidesmus indicus (L.) R. Br. ex Schult, Leucas aspera (Wild.), Plumbago zeylanica L and Tridax procumbens (L.) R. Br. ex Schult.

Frontiers in Microbiology, 2015
Herbal products derived from Hemidesmus indicus (L.) R. Br. ex Schult, Leucas aspera (Wild.), Plumbago zeylanica L and Tridax procumbens (L.) R. Br. ex Schult.
Kongari eSaritha, Angireddy eRajesh, Khanapur eManjulatha, Oruganti H Setty, Suresh eYenugu   +4 more
doaj   +1 more source

Kv11 (ether-à-go-go-related gene) voltage-dependent K⁺ channels promote resonance and oscillation of subthreshold membrane potentials. [PDF]

J Physiol, 2021
Matsuoka T, Yamasaki M, Abe M, Matsuda Y, Morino H, Kawakami H, Sakimura K, Watanabe M, Hashimoto K.   +8 more
europepmc   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Membrane potentials of cancer cells.pdf

, 2017
We discuss why the membrane potentials of cancer cells are often smaller than those of healthy cells, and why the stresses associated with reduced membrane potentials might not automatically cause destruction of cells by apoptosis.The fact that cytochrome c appears as a key intermediary both in cellular respiration and in apoptosis suggests that damage
openaire   +1 more source