Results 101 to 110 of about 438,564 (323)

Donnan potential and surface potential of a charged membrane

open access: yesBiophysical Journal, 1985
A model is presented for the electrical potential distribution across a charged biological membrane that is in equilibrium with an electrolyte solution. We assume that a membrane has charged surface layers of thickness d on both surfaces of the membrane, where the fixed charges are distributed at a uniform density N within the layers, and that these ...
Ohshima, H., Ohki, S.
openaire   +2 more sources

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

The Optimal Size of Stochastic Hodgkin-Huxley Neuronal Systems for Maximal Energy Efficiency in Coding of Pulse Signals

open access: yes, 2013
The generation and conduction of action potentials represents a fundamental means of communication in the nervous system, and is a metabolically expensive process.
Liu, Liwei, Yu, Lianchun
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

ON THE DETERMINATION OF ELASTIC POTENTIAL OF SPHERICAL RUBBER MEMBRANES

open access: yesStructural Mechanics of Engineering Constructions and Buildings, 2012
If one wants to make strength analysis of rubber membrane having large deformation, he must know the elastic potential. Having used potentials of Mooney and K.F.
N K Galimov   +2 more
doaj  

Photolipid excitation triggers depolarizing optocapacitive currents and action potentials

open access: yesNature Communications
Optically-induced changes in membrane capacitance may regulate neuronal activity without requiring genetic modifications. Previously, they mainly relied on sudden temperature jumps due to light absorption by membrane-associated nanomaterials or water ...
Carlos A. Z. Bassetto   +6 more
doaj   +1 more source

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