Results 181 to 190 of about 438,564 (323)

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

How and when to measure mitochondrial inner membrane potentials. [PDF]

Biophys J
Kowaltowski AJ, Abdulkader F.
europepmc   +1 more source

Metformin restores the mitochondrial membrane potentials in association with a reduction in TIMM23 and NDUFS3 in MPP+-induced neurotoxicity in SH-SY5Y cells. [PDF]

EXCLI J, 2019
Chanthammachat P, Dharmasaroja P.
europepmc   +1 more source

Membrane currents underlying the cholinergic slow excitatory post‐synaptic potential in the rat sympathetic ganglion.

, 1985
David A. Brown, A. A. Selyanko
openalex   +2 more sources

Characterization of the thermolysis products of Nafion membrane: A potential source of perfluorinated compounds in the environment [PDF]

, 2015
Mingbao Feng, Ruijuan Qu, Zhongbo Wei, Liansheng Wang, Ping Sun, Zunyao Wang   +5 more
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Calcium-Mediated Oscillation in Membrane Potentials and Atrial-Triggered Activity in Atrial Cells of Casq2^R33Q/R33Q Mutation Mice. [PDF]

Front Physiol, 2018
Zhang JC, Wu HL, Chen Q, Xie XT, Zou T, Zhu C, Dong Y, Xiang GJ, Ye L, Li Y, Zhu PL.   +10 more
europepmc   +1 more source

Caspase-8 Activation Precedes Alterations of Mitochondrial Membrane Potential during Monocyte Apoptosis Induced by Phagocytosis and Killing of Staphylococcus aureus

, 2004
Kazimierz Weęglarczyk, Jarosław Baran, Marek Zembala, J Pryjma   +3 more
openalex   +2 more sources

Fabrication of Hybrid Membranes Containing Nylon-11 and Organic Semiconductor Particles with Potential Applications in Molecular Electronics [PDF]

, 2019
María Elena Sánchez Vergara, Elizabeth Guevara‐Gutiérrez, Alejandra Arreola-Castillo, Alejandra Mendoza-Sevilla   +3 more
openalex   +1 more source