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Protein-Protein Interactions in Membranes

Protein & Peptide Letters, 2011
In this article we review the current status of our understanding of membrane mediated interactions from theory and experiment. Phenomenological mean field and molecular models will be discussed and compared to recent experimental results from dynamical neutron scattering and atomic force microscopy.
Armstrong, C.L.   +2 more
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The proteins of membranes

Journal of Colloid and Interface Science, 1977
Abstract Proteins constitute the largest fraction by weight of most membranes, and their properties are critical to membrane functions. A brief discussion is given of some salient theoretical and experimental advances of the last decade in our understanding of the structures of proteins in membranes, which have led to the fluid mosaic model of ...
openaire   +1 more source

Membrane cofactor protein

1992
MCP serves to down-regulate the activation of complement on host tissue. It performs this function by serving as a cofactor for the factor I-mediated cleavage of C3b and C4b. MCP is most likely an intrinsic regulator, i.e., it primarily protects its home cell.
M K, Liszewski, J P, Atkinson
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Locating protein in membranes

Chemistry and Physics of Lipids, 1972
I RECENTLY summarized X-ray diffraction data from some natural membranes to show that the original Danielli-Davson model is not valid for them1. A second widely-discussed structural model, having protein inserted into a lipid bilayer, was put forward as an alternative.
openaire   +4 more sources

Microseparation of membrane proteins

Journal of Separation Science, 2009
AbstractMembrane proteins are generally of natural low abundance and insoluble to aqueous solutions. Thus, investigation of membrane proteins is relatively hampered since efficient separation of membrane proteins are rather challenging. Microseparation approaches certainly play an essential role in fulfilling such demanding investigations due to their ...
Zhaowei, Zhang   +4 more
openaire   +2 more sources

Membrane-protein engineering

Trends in Biotechnology, 1997
Membrane proteins perform many of the essential functions required for life. They are often the targets of medicinal drugs and have many potential uses in biotechnological processes. Therefore our ability to understand them and manipulate their functions is both important and necessary to enable protein engineers to create 'designer' membrane proteins (
I, Mingarro, G, von Heijne, P, Whitley
openaire   +2 more sources

Membrane phosphoinositides and protein–membrane interactions

Amino Acids, 2013
Proteins with polybasic clusters bind to negatively charged phosphoinositides at the cell membrane. In this review, I have briefly discussed the types of phosphoinositides naturally found on membrane surfaces and how they recruit protein complexes for carrying out the process of signal transduction.
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Membrane Transport of Proteins

Nature New Biology, 1972
FACILITATED diffusion of small organic molecules across cell membranes is thought to be carrier-mediated in part because the process displays reaction kinetics. Models describing carrier transport assume that the transported molecule is associated with the membrane, reacting presumably with membrane proteins, and is then moved across the barrier.
C, Liebow, S S, Rothman
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Lipid Membranes for Membrane Proteins

2014
The molecular dynamics (MD) simulation of membrane proteins requires the setup of an accurate representation of lipid bilayers. This chapter describes the setup of a lipid bilayer system from scratch using generally available tools, starting with a definition of the lipid molecule POPE, generation of a lipid bilayer, energy minimization, MD simulation,
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The cell membrane and membrane proteins

2018
This chapter talks about biological membranes that have a lipid bilayer structure made up of a variety of different lipids held together by noncovalent bonds. It shows that lipids are arranged with their hydrophobic tails pointing to the middle of the bilayer and their hydrophilic sections to the outside.
Despo Papachristodoulou   +3 more
openaire   +1 more source

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