Results 61 to 70 of about 6,618,097 (286)
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Multilayered regulation of GluK3 kainate receptors is mediated by Neto subunits and zinc
Communications BiologyKainate receptors (KARs), a distinct subfamily of ionotropic glutamate receptors, are critical modulators of synaptic transmission and network excitability. Their function is intricately regulated by auxiliary subunits and endogenous ions.
Rajesh Vinnakota +4 more
doaj +1 more source
The rapid developments of membrane protein structure biology over the last two decades
BMC Biology, 2023 Membrane protein research has flourished in the past 20 years. Exciting technological innovations in structural biology, including cryoEM single-particle analysis and AI-based protein structure prediction, such as AlphaFold 2, have largely revolutionized
Lan Guan
doaj +1 more source
Inhibition of TRPP3 by calmodulin through Ca2+/calmodulin-dependent protein kinase II
Cell Insight, 2023 Transient receptor potential (TRP) polycystin-3 (TRPP3) is a non-selective cation channel activated by Ca2+ and protons and is involved in regulating ciliary Ca2+ concentration, hedgehog signaling and sour tasting.
Xiong Liu +6 more
doaj +1 more source
Tracking Membrane Protein Association in Model Membranes
PLoS ONE, 2009 Membrane proteins are essential in the exchange processes of cells. In spite of great breakthrough in soluble proteins studies, membrane proteins structures, functions and interactions are still a challenge because of the difficulties related to their hydrophobic properties.
Reffay, Myriam +7 more
openaire +8 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Protein Targeting to the Bacterial Cytoplasmic Membrane [PDF]
, 1999 Proteins that perform their activity within the cytoplasmic membrane or outside this cell boundary must be targeted to the translocation site prior to their insertion and/or translocation.
Fekkes, Peter +3 more
core +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Relative domain folding and stability of a membrane transport protein [PDF]
, 2014 There is a limited understanding of the folding of multidomain membrane proteins. Lactose permease (LacY) of Escherichia coli is an archetypal member of the major facilitator superfamily of membrane transport proteins, which contain two domains of six ...
Findlay, Heather E. +8 more
core +1 more source
Cornichons: Evolution, AMPA receptor modulation, and emerging roles beyond the nervous system
Brain DisordersCornichons are auxiliary proteins that regulate the functions of AMPA receptors (AMPARs), which mediate fast excitatory transmission in the central nervous system.
Pratibha Bharti +3 more
doaj +1 more source