Results 181 to 190 of about 8,544,371 (366)

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

Nature Protocols, 2014
A. Goehring, Chia-Hsueh Lee, Kevin H. Wang, J. C. Michel, D. P. Claxton, I. Baconguis, Thorsten Althoff, Suzanne Fischer, K. Garcia, E. Gouaux   +9 more
semanticscholar   +1 more source

Membrane protein structure

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2002
Dr.A.G. Lee, Philip L. Yeagle
openaire   +3 more sources

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Generation of Conformation-Specific Monoclonal Antibodies for Integral Membrane Proteins. [PDF]

Curr Protoc
Sheldon N, Dhandapani G, Kim J, Spangler CJ, Fang C, Park J, Rao P, Gouaux E.   +7 more
europepmc   +1 more source

Cell‐free synthesis of vesicular stomatitis virus proteins: translation of membrane‐bound polyribosomal mRNAs [PDF]

, 1975
Frances Toneguzzo, Hara P. Ghosh
openalex   +1 more source

Computational modeling of membrane proteins

Proteins: Structure, Function, and Bioinformatics, 2015
Julia Koehler Leman, M. Ulmschneider, Jeffrey J. Gray   +2 more
semanticscholar   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

The appearance of a protein in the human erythrocyte membrane during ageing [PDF]

, 1974
M. Kadlubowski, J. Robin Harris
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

DNA Tweezers with Replaceable Clamps for the Targeted Degradation of Cell Membrane Proteins. [PDF]

Pharmaceutics
Sun Y, Huang Y, Chen D, Hu S, Pan T, Liu Y, Wang R, Tan W.   +7 more
europepmc   +1 more source