Results 201 to 210 of about 4,599,169 (256)

Probing the Annular Lipid Belt of Membrane Proteins Using Native Mass Spectrometry. [PDF]

Methods Mol Biol
Kumar S, Laganowsky A.
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

VPS26A retromer complex and SNX27 mediate stress-induced Golgi bypass of membrane proteins. [PDF]

Nat Commun
Kim YJ, Lee C, Seo SK, Roh JW, Lee HR, Hwang SJ, Chang N, Choi HS, Shin DH, Kim HK, Kim HS, Cho HS, Cho HS, Lee JM, Gee HY, Lee MG, Noh SH.   +16 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Structural insights into MERS and SARS coronavirus membrane proteins. [PDF]

Commun Biol
Mann MK, Yin Y, Marsili S, Xie J, Doijen J, Miller R, Piassek M, van den Broeck N, Kariuki CK, de Gruyter HLM, Leijs AA, Snijder EJ, van Hemert MJ, Keustermans K, Van Gool M, Yu X, Loock MV, Koul A, Sharma S, Van Damme E, Abeywickrema P.   +20 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Membrane Permeability Drives the Extreme Potency of Fentanyl

JACS Au
Joseph Clayton, George J. Farmer, Jacqueline Glenn, Shailesh N. Mistry, J. Robert Lane, Lei Shi, Lidiya Stavitskaya, Meritxell Canals, Jana Shen   +8 more
doaj   +1 more source

Dual-Color Expansion Microscopy of Membrane Proteins Using Bioorthogonal Labeling. [PDF]

Nano Lett
Edwards S, Meineke B, Bauer S, Blom H, Elsässer S, Brismar H.   +5 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source