Results 181 to 190 of about 10,936,171 (356)

Integration of Membrane Proteins into the Outer Membrane of Diderm Bacteria by the BAM Complex. [PDF]

Chem Rev
Birtles D, Fenn KL, Machin JM, Radford SE, Ranson NA.   +4 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Toward Nanodisc Tailoring for SANS Study of Membrane Proteins. [PDF]

Bioengineering (Basel)
Batchu KC, Tully MD, Martel A.
europepmc   +1 more source

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

Nature Protocols, 2014
A. Goehring, Chia-Hsueh Lee, Kevin H. Wang, J. C. Michel, D. P. Claxton, I. Baconguis, Thorsten Althoff, Suzanne Fischer, K. Garcia, E. Gouaux   +9 more
semanticscholar   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Integrated Native Mass Spectrometry Imaging of Soluble and Membrane Proteins. [PDF]

J Am Chem Soc
Hale OJ, Cooper HJ.
europepmc   +1 more source

Structural Symmetry in Membrane Proteins.

Annual Review of Biophysics, 2015
L. Forrest
semanticscholar   +1 more source

Membrane protein biophysics [PDF]

Nature, 2009
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Dual-Color Expansion Microscopy of Membrane Proteins Using Bioorthogonal Labeling. [PDF]

Nano Lett
Edwards S, Meineke B, Bauer S, Blom H, Elsässer S, Brismar H.   +5 more
europepmc   +1 more source