Results 251 to 260 of about 2,118,036 (319)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Molecular contacts in self-assembling clusters of membrane proteins. [PDF]

Proc Natl Acad Sci U S A
Mandala VS, Fu Z, MacKinnon R.
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Ketoboronate as a Minimal Covalent-Reversible Tag for Targeted Lysosomal Degradation of Extracellular and Membrane Proteins. [PDF]

J Am Chem Soc
Pechalrieu D, Nogueira V, Qiu N, Racioppo B, Abegg D, Hay N, Adibekian A.   +6 more
europepmc   +1 more source

Impacts of heat and noncovalent bonding on interfacial property and structure of goat milk fat globule membrane proteins. [PDF]

NPJ Sci Food
Luo Y, Song Y, Su L, Zhou Y, Chen C, Du Z, Sun Y.   +6 more
europepmc   +1 more source

Proteomic Analysis Comparing Effect of Feeding Practices on the Milk Fat Globule Membrane Proteins from <i>Camelus dromedarius</i>. [PDF]

Foods
Masood A, Alanazi IO, Alfadda AA, Joy SS, Mazzotti F, Ousman OM, Benabdelkamel H.   +6 more
europepmc   +1 more source

FETCH enables fluorescent labeling of membrane proteins in vivo with spatiotemporal control in <i>Drosophila</i>. [PDF]

Proc Natl Acad Sci U S A
Rostam KD, Morano NC, Menon KP, Lopez DH, Shapiro L, Zinn K, Feng S, Mann RS.   +7 more
europepmc   +1 more source

Generation of Conformation-Specific Monoclonal Antibodies for Integral Membrane Proteins. [PDF]

Curr Protoc
Sheldon N, Dhandapani G, Kim J, Spangler CJ, Fang C, Park J, Rao P, Gouaux E.   +7 more
europepmc   +1 more source