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MAASTY: a (dis)ordered copolymer for structural determination of human membrane proteins in native nanodiscs. [PDF]

open access: yesNat Commun
Pugh CF   +9 more
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Membrane proteins and membrane proteomics

PROTEOMICS, 2008
Abstract Biological membranes form an essential barrier between living cells and their external environments, as well as serve to compartmentalize intracellular organelles within eukaryotes. The latter includes membranes that envelope the nucleus, the outer and inner membranes of the mitochondria, membrane cisternae complex of the ER,
Sandra, Tan   +2 more
openaire   +2 more sources

Topology of Membrane Proteins

Journal of Chemical Information and Computer Sciences, 2001
Integral membrane proteins play important roles in living cells. Due to difficulties of experimental techniques, theoretical approaches, i.e., topology prediction methods, are important for structure determination of this class of proteins. Here we show a detailed comparison of transmembrane topology prediction methods. According to this comparison, we
Gábor E. Tusnády, István Simon
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The proteins of membranes

Journal of Colloid and Interface Science, 1977
Abstract Proteins constitute the largest fraction by weight of most membranes, and their properties are critical to membrane functions. A brief discussion is given of some salient theoretical and experimental advances of the last decade in our understanding of the structures of proteins in membranes, which have led to the fluid mosaic model of ...
openaire   +1 more source

Protein-Protein Interactions in Membranes

Protein & Peptide Letters, 2011
In this article we review the current status of our understanding of membrane mediated interactions from theory and experiment. Phenomenological mean field and molecular models will be discussed and compared to recent experimental results from dynamical neutron scattering and atomic force microscopy.
Armstrong, C.L.   +2 more
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Membrane cofactor protein

1992
MCP serves to down-regulate the activation of complement on host tissue. It performs this function by serving as a cofactor for the factor I-mediated cleavage of C3b and C4b. MCP is most likely an intrinsic regulator, i.e., it primarily protects its home cell.
M K, Liszewski, J P, Atkinson
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Locating protein in membranes

Chemistry and Physics of Lipids, 1972
I RECENTLY summarized X-ray diffraction data from some natural membranes to show that the original Danielli-Davson model is not valid for them1. A second widely-discussed structural model, having protein inserted into a lipid bilayer, was put forward as an alternative.
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