Results 81 to 90 of about 8,472,623 (290)
The dynamics of plant plasma membrane proteins: PINs and beyond
Development, 2014 Plants are permanently situated in a fixed location and thus are well adapted to sense and respond to environmental stimuli and developmental cues. At the cellular level, several of these responses require delicate adjustments that affect the activity ...
C. Luschnig, G. Vert
semanticscholar +1 more source
How Carvedilol activates β2-adrenoceptors
Nature Communications, 2022 Carvedilol is among the most effective β-blockers for improving survival after myocardial infarction. Yet the mechanisms by which carvedilol achieves this superior clinical profile are still unclear.
Tobias Benkel +29 more
doaj +1 more source
CRC 1114 - Report Membrane Deformation by N-BAR Proteins: Extraction of membrane geometry and protein diffusion characteristics from MD simulations [PDF]
arXiv, 2017 We describe simulations of Proteins and artificial pseudo-molecules interacting and shaping lipid bilayer membranes. We extract protein diffusion Parameters, membrane deformation profiles and the elastic properties of the used membrane models in preparation of calculations based on a large scale continuum model.
arxiv
Membrane Lipids and the Conformations of Membrane Proteins [PDF]
The Journal of General Physiology, 1969 The general relations between protein conformation and the optical activity of peptide chromophores are outlined and applied to the analysis of the optical rotatory dispersion and circular dichroism of the plasma membranes of human erythrocytes and Ehrlich ascites carcinoma cells.
openaire +2 more sources
Membrane Fusion: Grappling with SNARE and SM Proteins
Science, 2009 The two universally required components of the intracellular membrane fusion machinery, SNARE and SM (Sec1/Munc18-like) proteins, play complementary roles in fusion.
T. Südhof, J. Rothman
semanticscholar +1 more source
Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery
Cell Reports, 2020 Summary: Autophagy is a catabolic process involving capture of cytoplasmic materials into double-membraned autophagosomes that subsequently fuse with lysosomes for degradation of the materials by lysosomal hydrolases.
Carlos M. Guardia +10 more
doaj
Membrane morphology induced by anisotropic proteins [PDF]
, 2010 There are a great many proteins that localize to and collectively generate curvature in biological fluid membranes. We study changes in the topology of fluid membranes due to the presence of highly anisotropic, curvature-inducing proteins. Generically, we find a surprisingly rich phase diagram with phases of both positive and negative Gaussian ...
arxiv +1 more source
Journal of the American Chemical Society, 2013 Structural studies of membrane proteins are still hampered by difficulties of finding appropriate membrane-mimicking media that maintain protein structure and function. Phospholipid nanodiscs seem promising to overcome the intrinsic problems of detergent-
F. Hagn +3 more
semanticscholar +1 more source
Informing β-cell regeneration strategies using studies of heterogeneity
Molecular Metabolism, 2019 Background: Current therapeutic strategies for type 1 (T1DM) and type 2 diabetes mellitus (T2DM) rely on increasing or substituting endogenous insulin secretion in combination with lifestyle changes.
Daniela Nasteska +3 more
doaj
Rotational Diffusion of Membrane Proteins: Characterization of Protein-Protein Interactions in Membranes [PDF]
Biophysical Journal, 2012 It has long been appreciated that the rotational diffusion coefficient (Dr) and hence the rotational correlation time (τr) of a transmembrane protein about its membrane normal axis is predicted to be highly sensitive to its cylindrical radius (e.g., Saffman and Delbruck (1)). Due to the highly viscous nature of a cellular membrane or a membrane bilayer,
openaire +3 more sources