Results 51 to 60 of about 1,558,886 (314)

The Borrelia afzelii outer membrane protein BAPKO_0422 binds human Factor-H and is predicted to form a membrane-spanning beta-barrel [PDF]

, 2015
The deep evolutionary history of the Spirochetes places their branch point early in the evolution of the diderms, before the divergence of the present day Proteobacteria.
Brown, G., Bingham, Richard, Bingham, R.J., Stejskal, Lenka, Laity, Peter R., Dyer, A., Laity, P.R., Stejskal, L., Dyer, Adam, Brown, Gemma   +9 more
core   +1 more source

Supervised multi-frame dual-channel denoising enables long-term single-molecule FRET under extremely low photon budget

Nature Communications
Camera-based single-molecule techniques have emerged as crucial tools in revolutionizing the understanding of biochemical and cellular processes due to their ability to capture dynamic processes with high precision, high-throughput capabilities, and ...
Yu Miao, Yuxiao Cheng, Yushi Xia, Yongzhen Hei, Wenjuan Wang, Qionghai Dai, Jinli Suo, Chunlai Chen   +7 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Membrane biofouling and scaling in forward osmosis membrane bioreactor

, 2012
The forward osmosis membrane bioreactor (FOMBR) has received much attention recently. Due to the high rejection nature of FO membranes, the biomass, dissolved organic and inorganic compounds retained in the bioreactor could cause membrane fouling by ...
Fane, Anthony Gordon, Lay, Winson Chee Loong, Tang, C, Wang, Rong, Chou, Shuren, Tang, Chuyang Y., Wang, R, Fane, AG, Loong, WLC, Zhang, J, Chou, S, Zhang, Jinsong   +11 more
core   +1 more source

Microscopic simulation of membrane molecule diffusion on corralled membrane surfaces [PDF]

, 2008
The current understanding of how receptors diffuse and cluster in the plasma membrane is limited. Data from single-particle tracking and laser tweezer experiments have suggested that membrane molecule diffusion is affected by the presence of barriers ...
Edwards, Jeremy S., Vlachos, Dionisios G., Tribe, Roger, Plechac, Petr, Niehaus, Anne Marie S.   +4 more
core   +1 more source

Deep learning based local feature classification to automatically identify single molecule fluorescence events

Communications Biology
Long-term single-molecule fluorescence measurements are widely used powerful tools to study the conformational dynamics of biomolecules in real time to further elucidate their conformational dynamics.
Shuqi Zhou, Yu Miao, Haoren Qiu, Yuan Yao, Wenjuan Wang, Chunlai Chen   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Alignment of helical membrane protein sequences using AlignMe

, 2013
Few sequence alignment methods have been designed specifically for integral membrane proteins, even though these important proteins have distinct evolutionary and structural properties that might affect their alignments.
René Staritzbichler, Stamm, Marcus, Staritzbichler, René, Khafizov, Kamil, Marcus Stamm (384964), Khafizov, K., Kamil Khafizov, Lucy R Forrest, René Staritzbichler (2667769), Staritzbichler, R., Marcus Stamm, Forrest, L., Forrest, Lucy R., Stamm, M., Kamil Khafizov (384965), Lucy R. Forrest (384966)   +15 more
core   +1 more source

The roles of migrasome in development

Cell Insight
Migrasomes are newly identified vesicular structures that mainly come from the ends and crosspoints of retracting fibers in moving cells. Their creation is closely linked with cell movement and goes through three key steps: Nucleation, Maturation, and ...
Zhaocheng Zhai, Boqi Liu, Li Yu
doaj   +1 more source