Several nutrient permeases have been identified in yeast, which combine a transport and receptor function, and are called transceptors. The Gap1 general amino acid permease and the Mep2 ammonium permease mediate rapid activation by amino acids and by ...
Griet Van Zeebroeck+3 more
doaj +1 more source
Import to the inner nuclear membrane:a structural perspective [PDF]
In all eukaryotic cell, form yeast to humans, the Nuclear Pore Complexes provide the main gateway to the nuclear interior. While the transport of soluble cargo’s in and out of the nucleus is relatively well understood, the transport of membrane proteins ...
Hapsari, Rizqiya Astri
core +2 more sources
An Arabidopsis peptide transporter is a member of a new class of membrane transport proteins.
An Arabidopsis peptide transport gene was cloned from an Arabidopsis cDNA library by functionally complementing a yeast peptide transport mutant.
H. Steiner+5 more
semanticscholar +1 more source
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
The dynamic organization of signaling cascades inside primary cilia is key to signal propagation. Yet little is known about the dynamics of ciliary membrane proteins besides a possible role for motor-driven Intraflagellar Transport (IFT). To characterize
Fan Ye+5 more
doaj +1 more source
Regulation of hepatic transport of bile salt. Effect of protein synthesis inhibition on excretion of bile salts and their binding to liver surface membrane fractions. [PDF]
Marı́a Cristina González+2 more
openalex +1 more source
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita+1 more
wiley +1 more source
Selektive Wirkungen von Lindan (γ-1,2,3,4,5,6-Hexachlorcyclohexan) auf Photosynthese, Aminosäure — Membrantransport und Proteinsynthese bei Anacystis nidulans / Selective Effects of Lindane (γ-1,2,3,4,5,6 Hexachlorocyclohexane) on Photosynthesis, Membrane Transport of Amino Acids and Protein Synthesis in Anacystis nidulans [PDF]
W. Simonis, Johanna Lee-Kaden
openalex +1 more source
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source
Reconstitution of specific Na+‐dependent D‐glucose transport in liposomes by triton X‐100‐extracted proteins from purified brush border membranes of rabbit kidney cortex [PDF]
Robert K. Crane, P. Malathi, H. Preiser
openalex +1 more source