Results 41 to 50 of about 360,735 (316)

A cytosolic factor mediating membrane recruitment of AP-1 clathrin adaptors [PDF]

, 2008
Transport of cargo within the endocytic and secretory pathway is generally mediated by coated vesicles. These vesicles are formed through the recruitment of cytosolic coat proteins to the donor membrane that act as a scaffold to form coated buds and ...
Suri, Gregor
core   +1 more source

Porphyromonas gingivalis Outer Membrane Vesicles Mediate Coaggregation and Piggybacking of Treponema denticola and Lachnoanaerobaculum saburreum

International Journal of Dentistry, 2013
Porphyromonas gingivalis sheds outer membrane vesicles that contain several virulence factors, including adhesins. In this study, we investigated the ability of P.
Daniel Grenier
doaj   +1 more source

The Contribution of Membrane Vesicles to Bacterial Pathogenicity in Cystic Fibrosis Infections and Healthcare Associated Pneumonia

Frontiers in Microbiology, 2020
Almost all bacteria secrete spherical membranous nanoparticles, also referred to as membrane vesicles (MVs). A variety of MV types exist, ranging from 20 to 400 nm in diameter, each with their own formation routes.
Jolien Vitse, Bart Devreese
doaj   +1 more source

Secretory vesicles are preferentially targeted to areas of low molecular SNARE density [PDF]

, 2012
Intercellular communication is commonly mediated by the regulated fusion, or exocytosis, of vesicles with the cell surface. SNARE (soluble N-ethymaleimide sensitive factor attachment protein receptor) proteins are the catalytic core of the secretory ...
Weiping Lu (120665), Dun, Alison R., Lu, Weiping, Rory R. Duncan (120667), Weiping Lu, Gabriel J. Lord (120664), Colin Rickman (120669), Andrew Dunn, Gabriel J Lord, Martin, Kirsty J, Lei Yang (102719), Qiu, Zhen, Rickman, Colin; id_orcid, Kirsty J Martin, Lei Yang, Duncan, Rory R, Duncan, Rory R., Alison R. Dun (120660), Zhen Qiu (120662), Rickman, Colin, Dun, Alison, Qiu, Zhen; id_orcid, Colin Rickman, Rory R Duncan, Lord, Gabriel J, Kirsty J. Martin (120661), Alison R Dun, Lord, Gabriel J., Yang, Lei, Martin, Kirsty J., Andrew Dunn (120663), Dunn, Andrew, Zhen Qiu   +32 more
core   +1 more source

Membrane Vesicles as Drug Delivery Systems: MISEV, In Vivo Fluorescence Imaging and Tracking, Specific Tissue Targeting, and Therapeutic Application in Diseases

Pharmaceutics
In the last decade, notable developments have occurred regarding the application of membrane vesicles—encompassing extracellular vesicles (EVs, including exosomes, microvesicles, apoptotic bodies, and others), self-organized cellular-membrane-derived ...
Ying Qin, Hongda Zhuang, Xiaoyong Ren, Mengyi Lan, Shuoshuo Fan, Zhitao Qiu, Junfang Zhao, Yong Chen   +7 more
doaj   +1 more source

Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes

, 2013
Introduction: In recent years, there has been an exponential increase in the number of studies aiming to understand the biology of exosomes, as well as other extracellular vesicles.
Szabó, Tamas G, Szabó, Tamás G., Buzás, Edit Irén, Lötvall, Jan, Jan Lötvall, Lässer, Cecilia, Dianzani, Irma, Irma Dianzani, Edit I. Buzás, Jan Lötvall, Buzás, Edit I, Maria Eldh, Crescitelli, Rossella, Kittel, Ágnes, Eldh, Maria, Rossella Crescitelli, Agnes Kittel, Tamas G. Szabó, Edit I. Buzás, Cecilia Lässer, Tamas G. Szabó, Cecilia Lässer   +21 more
core   +1 more source

Munc 18-1 Protein Molecules Move between Membrane Molecular Depots Distinct from Vesicle Docking Sites [PDF]

, 2013
Four evolutionarily conserved proteins are required for mammalian regulated exocytosis: three SNARE proteins, syntaxin, SNAP-25, and synaptobrevin, and the SM protein, Munc18-1. Here, using single-molecule imaging, we measured the spatial distribution of
Rickman, Colin, Lu, Weiping, Yang, Lei, Hamilton, Charlotte, Smyth, Annya M., Cousin, Michael A., Rickman, Colin; id_orcid, Martin, Kirsty J., Duncan, Rory R., Cousin, Michael A.; id_orcid   +9 more
core   +1 more source

Coupled Effects of Mechanics, Geometry, and Chemistry on Bio-Membrane Behavior [PDF]

, 2013
Lipid bilayer membranes are models for cell membranes--the structure that helps regulate cell function. Cell membranes are heterogeneous, and the coupling between composition and shape gives rise to complex behaviors that are important to regulation ...
Giang, Ha Thanh
core   +1 more source

Bacterial outer membrane vesicles and vaccine applications

, 2014
Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of “self ...
Jose Luis Perez, Sonsire Fernández, Fernandez, Sonsire, Daniel eCardoso, Armando Acosta, Rosenqvist, Einar, Armando eAcosta, Concepcion eCampa, Campa, Concepcion, Luis eGarcia, Daniel Cardoso, Cardoso, Daniel, Zayas, Caridad, Luis Garcia, Caridad eZayas, Concepcion Campa, Caridad Zayas, Acevedo, Reinaldo, Reinaldo eAcevedo, Sarmiento, Maria Elena, Garcia, Luis, Valerie A Ferro, Sonsire eFernandez, Ferro, Valerie, Einar Rosenqvist, Acosta, Armando, Reinaldo Acevedo, Perez, Jose Luis, Einar eRosenqvist, Valerie A. Ferro, Maria Elena Sarmiento   +30 more
core   +1 more source

Molecular Aspects of Secretory Granule Exocytosis by Neurons and Endocrine Cells [PDF]

, 1994
Neuronal communication and endocrine signaling are fundamental for integrating the function of tissues and cells in the body. Hormones released by endocrine cells are transported to the target cells through the circulation.
MANFRED GRATZL, Gratzl, Manfred
core   +1 more source