Results 111 to 120 of about 4,622,763 (348)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Ceramic Nanofiltration Membranes: Creating Nanopores by Calcination of Atmospheric-Pressure Molecular Layer Deposition Grown Titanicone Layers

open access: yesMembranes
Ceramic membrane technology, whether applied as a stand-alone separation technology or in combination with energy-intensive approaches like distillation, is a promising solution for lower energy alternatives with minimal carbon footprints. To improve the
Harpreet Sondhi   +7 more
doaj   +1 more source

Membranous Nephropathy

open access: yesJournal of Clinical Medicine
Membranous nephropathy is a glomerular disease that may be caused by exogenous risk factors in genetically predisposed individuals (primary MN) or may be associated with other autoimmune diseases, drug exposure, or cytotoxic agents (secondary MN). Primary membranous nephropathy (PMN) is an autoimmune disease in which antigens—mainly the phospholipase ...
openaire   +3 more sources

Development of extra-embryonic membranes and fluid compartments [PDF]

open access: yes, 2001
An account of the development of extra-embryonic membranes in the embryo of poultry. The roles of these membranes in the transfer of water from albumen to yolk and to embryonic tissue is ...
Baggott, Glenn K.
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effect of Cross-linking on Antifouling Properties for PVDF-g-PACMO Membranes

open access: yesCailiao gongcheng, 2017
In order to enhance the capability of resistant to protein adsorption of the copolymer membrane of polyacryloylmorpholine-graft-acryloylmorpholine(PVDF-g-PACMO), a crosslinking agent of ethylene glycoldimethacrylate(EGDMA) was added to prepare the ...
FENG Qian-qian   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Preparation of a self‐supported zeolite glass composite membrane for CO2/CH4 separation

open access: yesSmart Molecules
The low porosity of metal‐organic framework glass makes it difficult to prepare membranes with high permeability. To solve this problem, we fabricated a series of self‐supported zeolite glass composite membranes with different 4A zeolite loadings using ...
Dudu Li   +5 more
doaj   +1 more source

Self-avoiding Tethered Membranes at the Tricritical Point

open access: yes, 1995
The scaling properties of self-avoiding tethered membranes at the tricritical point (theta-point) are studied by perturbative renormalization group methods. To treat the 3-body repulsive interaction (known to be relevant for polymers), new analytical and
Abraham   +24 more
core   +3 more sources

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