Results 111 to 120 of about 3,092,461 (356)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Research Progress in Flexible Wearable Strain Sensors Based on Polydimethylsiloxane

Cailiao gongcheng, 2018
Traditional electronic strain sensors based on metal and semiconductor materials have poor flexibility and wear-ability, which are not applicable for stretchable sensors.
JIN Xin, CHANG Xu-dong, WANG Wen-yu, ZHU Zheng-tao, LIN Tong   +4 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Ion and Water Transports in Double Gyroid Nanochannels Formed by Block Copolymer Anion Exchange Membranes

Batteries
Mechanically improved polymeric membranes with high ionic conductivity (IC) and good permeability are highly desired for next-generation anion exchange membranes (AEMs) in order to reduce Ohmic losses and enhance water management in alkaline membrane ...
Karim Aissou, Maximilien Coronas, Jason Richard, Erwan Ponsin, Sambhav Vishwakarma, Eddy Petit, Bertrand Rebiere, Camille Bakkali-Hassani, Stéphanie Roualdes, Damien Quemener   +9 more
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Microwaves induced epitaxial growth of urchin like MIL-53(Al) crystals on ceramic supports

Scientific Reports
Shaping Metal–Organic Frameworks (MOFs) poses a significant challenge for their widespread application on a large scale. In particular, a precise control over crystal orientation and arrangement on substrates are expected to provide exiting opportunities
Limor Ben Neon, Martin Drobek, Mikhael Bechelany, Bertrand Rebiere, Anne Julbe   +4 more
doaj   +1 more source

Crystalline Structures and Properties of Uniaxial Oriented Poly(ethylene chlorotrifluoroethylene) Fiber

Cailiao gongcheng, 2016
Uniaxial oriented poly (ethylene chlorotrifluoroethylene) (ECTFE) fibers were prepared by the melt spinning method using ECTFE resin as the fiber-forming polymer.
PAN Jian, XIAO Chang-fa, ZHAO Jian, HUANG Qing-lin, REN Qian   +4 more
doaj   +1 more source

BH3 Domains of BH3-Only Proteins Differentially Regulate Bax-Mediated Mitochondrial Membrane Permeabilization Both Directly and Indirectly [PDF]

, 2005
Tomomi Kuwana, Lisa Bouchier‐Hayes, Jerry E. Chipuk, Christine Bonzon, Barbara Sullivan, Douglas R. Green, Donald D. Newmeyer   +6 more
openalex   +1 more source

Nanoparticles functionalized ceramic membranes: fabrication, surface modification, and performance

, 2021
Dina Ewis, Norhan Ashraf Ismail, MhdAmmar Hafiz, Abdelbaki Benamor, Alaa H. Hawari   +4 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source