Results 91 to 100 of about 576,024 (313)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Predicting Transdermal Fentanyl Delivery Using Mechanistic Simulations for Tailored Therapy

Frontiers in Pharmacology, 2020
Transdermal drug delivery is a key technology for administering drugs. However, most devices are “one-size-fits-all”, even though drug diffusion through the skin varies significantly from person-to-person. For next-generation devices, personalization for
Thijs Defraeye, Flora Bahrami, Flora Bahrami, Lu Ding, Lu Ding, Riccardo Innocenti Malini, Alexandre Terrier, René M. Rossi   +7 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Enhanced antifouling and separation capabilities of polydopamine@Ce-MOF functionalized PES ultrafiltration membrane

npj Clean Water
The need for antifouling membranes is substantial due to fouling’s negative impact on the effectiveness and durability of ultrafiltration membranes.
Dana Kadadou, Thanigaivelan Arumugham, Lina Tizani, Shadi W. Hasan   +3 more
doaj   +1 more source

Efficient and simultaneous capture of iodine and methyl iodide achieved by a covalent organic framework

Nature Communications, 2022
Radioactive molecular iodine (I2) and methyl iodide (CH3I) coexist in the off-gas stream of nuclear power plants at low concentrations and only few adsorbents can effectively adsorb low-concentration I2 and CH3I simultaneously.
Yaqiang Xie, Tingting Pan, Qiong Lei, Cailing Chen, Xinglong Dong, Youyou Yuan, Walid Al Maksoud, Long Zhao, Luigi Cavallo, Ingo Pinnau, Yu Han   +10 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Comparison of anionic membranes used to concentrate nitric acid to beyond the azeotropic mixture [PDF]

The electrolysis of concentrated nitric acid solutions was carried out in an electrochemical cell with parallel plates (FM01-LC ICI). An anionic membrane that permits the migration of nitrate ions under the influence of an electrical field separated the ...
Field, Robert, Ponce de Leon, Carlos
core   +1 more source

Dual function filtration and catalytic breakdown of organic pollutants in wastewater using ozonation with titania and alumina membranes [PDF]

, 2011
Water recycling via treatment from industrial and/or municipal waste sources is one of the key strategies for resolving water shortages worldwide. Polymer membranes are effective at improving the water quality essential for recycling, but depend on ...
Gayle Morris, Hu, Yaoxin, Zhu, Bo, Jin, Wanqin, Duke, Mikel, Gray, Stephen R, Wanqin Jin, Stephen Kennedy, Morris, Gayle E, Stephen Gray, Yaoxin Hu, Milne, Nicholas A, Gray, Stephen, Kennedy, Stephen, Nicholas Milne, Bo Zhu, Mikel Duke   +16 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Biomimetic Approaches for Membrane Technologies

Separation & Purification Reviews, 2015
Membrane technology is the dominant process in water treatment. However, the operation cost of membranes cannot be decreased unless the amount of fouling, the “Achilles heel” of membranes, and energy consumed are cut. The high energy requirements in commercial nanofiltration, reverse osmosis and forward osmosis technologies lead researchers to develop ...
Sengur-Tasdemir, Reyhan, Aydin, Sevcan, Turken, Turker, Genceli, Esra Ates, Koyuncu, Ismail   +4 more
openaire   +2 more sources