Results 231 to 240 of about 25,462 (288)

A Network Pharmacology and Experimental Validation Strategy for Hypoglycemic Study of Lonicerae Japonicae Flos on Diabetes

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT As diabetes has become an important public health issue, Lonicerae Japonicae Flos (LJF) had gradually attracted increasing attention on diabetes. This study aimed to investigate the hypoglycemic ingredients and underlying mechanisms of LJF in diabetes using an integrated strategy of network pharmacology, molecular docking and experimental ...
Zhang Nan   +5 more
wiley   +1 more source

Clinical significance of renal histological diagnosis in patients with type 2 diabetes and proteinuria atypical for diabetic nephropathy

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 5, Page 781-790, May 2026.
ABSTRACT Background/Aim Most patients with proteinuria are considered to have typical diabetic nephropathy (DN). However, when proteinuria occurs without diabetic retinopathy, with hematuria, or persists despite strict glycemic and blood pressure control, it is considered atypical for DN and warrants further evaluation for non‐DN via kidney biopsy ...
Shogo Kuwagata   +16 more
wiley   +1 more source

The Risk Factors for Placental Abruption in Preeclamptic Pregnancies: A Retrospective Case–Control Study

open access: yesJournal of Obstetrics and Gynaecology Research, Volume 52, Issue 5, May 2026.
ABSTRACT Aim Preeclampsia poses a high‐risk factor for placental abruption. The precise understanding of the accompanying symptoms and disease phenotype of preeclampsia, in order to promptly identify the occurrence of placental abruption in preeclamptic women, remains unclear.
Kechen Li   +6 more
wiley   +1 more source

From Cure to Complexity: Post‐SVR Liver and Metabolic Trajectories in Diabetic Patients

open access: yesLiver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background and Aims The long‐term impact of HCV cure on hepatic and metabolic outcomes in patients with type 2 diabetes (T2D) remains insufficiently defined. This study evaluated T2D‐related vascular complications, liver disease progression and overall survival over 9 years of follow‐up, also exploring genetic variability contribution ...
Clelia Asero   +14 more
wiley   +1 more source

Aberrant DNMTs Promote TXNIP Upregulation and Ovarian Fibrosis in PCOS

open access: yesThe FASEB Journal, Volume 40, Issue 7, 15 April 2026.
In a rat model of DHEA/DHT‐induced PCOS and in granulosa cells (GCs), upregulated DNMT1, DNMT3A, and DNMT3B inhibit TXNIP degradation, leading to TXNIP accumulation, which drives ovarian fibrosis and tissue injury. ABSTRACT Hyperandrogenism and elevated thioredoxin‐interacting protein (TXNIP) are potential causes of infertility in women with polycystic
Yajing Weng   +12 more
wiley   +1 more source

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