Results 121 to 130 of about 486,459 (304)
Report to the Community 2007 [PDF]
, 2007 Examines the impact and achievements of the foundation over the past year in the areas of economic transformation, education, early childhood and youth development, neighborhoods, and the ...
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Advanced Science, EarlyView.Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang +10 more
wiley +1 more source
Representing and Reconstructing Memories of the World Wars in India
RIHA Journal, 2017 This paper examines the material memorialization of the World Wars in India by looking at the India Gate, the archway located at the center of the Indian national capital, New Delhi. Although dedicated to soldiers who lost their lives in World War I, the
Jeychandran, Neelima
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Integrative Approaches to Treating Cellular Senescence in Kidney Disease
Advanced Science, EarlyView.ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa +3 more
wiley +1 more source
Advanced Science, EarlyView.Cell‐sized high‐frequency ultrasound using a lithium niobate transducer, previously ignored in reactive oxygen species (ROS) production, generated intracellular ROS at frequencies higher than conventionally used. The intracellular generation of ROS by cell‐sized high‐frequency ultrasound revealed in this study is expected to be applied to innovative ...
Kotaro Fujishiro +4 more
wiley +1 more source
Historic Preservation Program newsletter [PDF]
, 2017 2017. UNIVERSITY OF VERMONT HISTORIC PRESERVATION PROGRAM HISTORY DEPARTMENT - WHEELER HOUSE - BURLINGTON, VERMONThttps://scholarworks.uvm.edu/hpnewsletter/1009/thumbnail ...
Historic Preservation Program newsletter,
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Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Advanced Science, EarlyView.Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
The Generation of Memory: Reflections on the “Memory Boom” in Contemporary Historical Studies [PDF]
, 2012 Jay Winter delivered the following in the form of a lecture at the Canadian War Museum on 31 October 2000. A distinguished academic, Winter has been writing about the cultural history of the First World War for nearly three decades.
Winter, Jay
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Advanced Science, EarlyView.This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang +16 more
wiley +1 more source
‘Forebears’, ‘saints’ and ‘martyrs’: the politics of commemoration in Bulgaria in the 1880s and 1890s [PDF]
, 2008 Book description: The relationship between states, societies, and individuals in Central and Eastern Europe has been characterised by periods of change and redefinition.
Detchev, S.
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